Solu-cortef and Avandia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Solu-cortef (hydrocortisone sodium succinate) and Avandia (rosiglitazone maleate). Common drug interactions include abscess among females and myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Solu-cortef and Avandia. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Solu-cortef?

Solu-cortef has active ingredients of hydrocortisone sodium succinate. eHealthMe is studying from 7,983 Solu-cortef users. Check the latest studies of Solu-cortef.

What is Avandia?

Avandia has active ingredients of rosiglitazone maleate. It is often used in diabetes. eHealthMe is studying from 142,155 Avandia users. Check the latest studies of Avandia.

On Jul, 06, 2026

11 people who take Solu-cortef and Avandia together, and have interactions are studied.

Solu-cortef and Avandia drug interactions.

What are the common drug interactions of Solu-Cortef and Avandia, by gender? *:

female:

Abscess (pus)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Asthma
Blood glucose increased
Bronchitis acute (acute inflammation of the mucous membrane in the bronchial tubes)
Cardiac valve disease (heart valve disease)
Cardiomegaly (increased size of heart than normal)
Cardiomyopathy (weakening of the heart muscle)
Cardiovascular disorder (heart diseases)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

male:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nausea (feeling of having an urge to vomit)
Anxiety
Arrhythmia (irregular heartbeat)
Ascites (accumulation of fluid in the abdominal cavity)
Blood triglycerides increased
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cardiac failure congestive
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cardiomegaly (increased size of heart than normal)

What are the common drug interactions of Solu-Cortef and Avandia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Blood aldosterone increased
Blood alkaline phosphatase increased
Blood amylase increased
Blood bilirubin increased
Blood corticotrophin increased
Blood glucose increased
Blood sodium decreased
Blood uric acid decreased
Chest pain

50-59:

Chest pain
Dyspnoea (difficult or laboured respiration)
Asthenia (weakness)
Cardiac failure congestive
Abscess (pus)
Asthma
Blood glucose increased
Bronchitis acute (acute inflammation of the mucous membrane in the bronchial tubes)
Cardiomegaly (increased size of heart than normal)
Cardiomyopathy (weakening of the heart muscle)

60+:

Anaemia (lack of blood)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Nausea (feeling of having an urge to vomit)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Platelet count decreased
Pyrexia (fever)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
White blood cell count decreased
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Cardiac valve disease (heart valve disease)

What are the existing conditions these people have? *

Type 2 Diabetes: 3 people, 27.27%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 18.18%
Upper Respiratory Tract Infection: 1 person, 9.09%
Transplant Rejection (a transplant material is not worked): 1 person, 9.09%
Pleural Effusion (water on the lungs): 1 person, 9.09%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 9.09%
Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 1 person, 9.09%
High Blood Pressure: 1 person, 9.09%
Chest Pain: 1 person, 9.09%
Adrenocortical Insufficiency Acute (suddenly adrenal glands do not produce adequate amounts of steroid hormones): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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