Solu-cortef and Cytosar-u drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Solu-cortef (hydrocortisone sodium succinate) and Cytosar-u (cytarabine). Common drug interactions include ataxia among females and convulsions among males.

The phase IV clinical study analyzes what interactions people have when they take Solu-cortef and Cytosar-u. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Solu-cortef?

Solu-cortef has active ingredients of hydrocortisone sodium succinate. eHealthMe is studying from 7,983 Solu-cortef users. Check the latest studies of Solu-cortef.

What is Cytosar-u?

Cytosar-u has active ingredients of cytarabine. eHealthMe is studying from 586 Cytosar-u users. Check the latest studies of Cytosar-u.

On Jul, 28, 2026

16 people who take Solu-cortef and Cytosar-u together, and have interactions are studied.

Solu-cortef and Cytosar-u drug interactions.

What are the common drug interactions of Solu-Cortef and Cytosar-U, by gender? *:

female:

Ataxia (loss of full control of bodily movements)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Streptococcal sepsis (whole body inflammation by streptococcal)
Coma (state of unconsciousness lasting more than six hours)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Mucosal inflammation (infection of mucous membrane)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)

male:

Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Dementia (madness)
Partial seizures (seizures which affect only a part of the brain at onset)
Thyroiditis acute (rapid inflammation of thyroid gland)
Thyrotoxicosis (a morbid condition due to over activity of the thyroid gland)
Toxic encephalopathy (a degenerative neurologic disorder caused by exposure to toxic substances)
Cellulitis (infection under the skin)
Erythema (redness of the skin)
Gingivitis (inflammation of gums)
Leukaemia relapse (failing of blood cancer or bone marrow cancer)

What are the common drug interactions of Solu-Cortef and Cytosar-U, by age (0-1 to 60+)? *:

0-1:

Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)

2-9:

Encephalopathy (functioning of the brain is affected by some agent or condition)
Paralysis flaccid (abnormal condition characterized by the weakening or the loss of muscle tone)
Partial seizures (seizures which affect only a part of the brain at onset)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Ataxia (loss of full control of bodily movements)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Streptococcal sepsis (whole body inflammation by streptococcal)
Coma (state of unconsciousness lasting more than six hours)

10-19:

Cellulitis (infection under the skin)
Erythema (redness of the skin)
Gingivitis (inflammation of gums)
Leukaemia relapse (failing of blood cancer or bone marrow cancer)
Neck swelling
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Neutropenia (an abnormally low number of neutrophils)
Paralysis flaccid (abnormal condition characterized by the weakening or the loss of muscle tone)
Partial seizures (seizures which affect only a part of the brain at onset)
Thyroiditis acute (rapid inflammation of thyroid gland)

20-29:

n/a

30-39:

Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Mucosal inflammation (infection of mucous membrane)

40-49:

n/a

50-59:

n/a

60+:

Dementia (madness)
Toxic encephalopathy (a degenerative neurologic disorder caused by exposure to toxic substances)

What are the existing conditions these people have? *

Burkitt's Lymphoma (cancer of the lymphatic system): 2 people, 12.50%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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