Solu-cortef and Mobic drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Solu-cortef (hydrocortisone sodium succinate) and Mobic (meloxicam). Common drug interactions include psoriasis among females and pruritus among males.

The phase IV clinical study analyzes what interactions people have when they take Solu-cortef and Mobic. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Solu-cortef?

Solu-cortef has active ingredients of hydrocortisone sodium succinate. eHealthMe is studying from 7,983 Solu-cortef users. Check the latest studies of Solu-cortef.

What is Mobic?

Mobic has active ingredients of meloxicam. It is often used in arthritis. eHealthMe is studying from 26,684 Mobic users. Check the latest studies of Mobic.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

27 people who take Solu-cortef and Mobic together, and have interactions are studied.

Solu-cortef and Mobic drug interactions.

What are the common drug interactions of Solu-Cortef and Mobic, by gender? *:

female:

Psoriasis (immune-mediated disease that affects the skin)
Pyelonephritis (inflammation of kidney caused by bacteria)
Renal failure (kidney dysfunction)
Sinusitis (inflammation of sinus)
Tooth infection
Urinary tract infection
Abnormal faeces (abnormal stool)
Acinetobacter bacteraemia (infection of bacteria)
Arthralgia (joint pain)
Aspartate aminotransferase increased

male:

Pruritus (severe itching of the skin)
Chest discomfort
Fatigue (feeling of tiredness)
Infusion site rash
Poor quality sleep
Spinal fracture (fracture in one of vertebrae)
Endocarditis (inflammation in heart muscle)
Muscle spasms (muscle contraction)
Osteomyelitis (infection of bone)
Restlessness (not able to rest)

What are the common drug interactions of Solu-Cortef and Mobic, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Endocarditis (inflammation in heart muscle)
Osteomyelitis (infection of bone)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Scoliosis (a medical condition in which a person's spine is curved from side to side)

20-29:

n/a

30-39:

Back pain
Chest pain
Abnormal faeces (abnormal stool)
Alanine aminotransferase increased
Anaemia (lack of blood)
Arthralgia (joint pain)
Aspartate aminotransferase increased
Blood bilirubin increased
Blood lactate dehydrogenase increased
Blood pressure systolic increased

40-49:

Gait disturbance
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Heart valve incompetence (heart's valves do not work correctly)
Hyperhidrosis (abnormally increased sweating)
Hyperkalaemia (damage to or disease of the kidney)
Hypertension (high blood pressure)
Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries))
Ileus (a painful obstruction of the ileum or other part of the intestine)

50-59:

Depression
Disturbance in attention
Dizziness
Drug ineffective
Erythema (redness of the skin)
Eye infection fungal
Flushing (the warm, red condition of human skin)
Heart rate increased
Hyperhidrosis (abnormally increased sweating)
Hypertension (high blood pressure)

60+:

Sepsis (a severe blood infection that can lead to organ failure and death)
Septic shock (shock due to blood infection)
Asthenia (weakness)
Cardiac failure
Chills (felling of cold)
Cough
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Disease progression
Duodenal ulcer
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 7 people, 25.93%
Type 2 Diabetes: 4 people, 14.81%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 14.81%
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 4 people, 14.81%
Constipation: 4 people, 14.81%
Neuropathy Peripheral (surface nerve damage): 3 people, 11.11%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 11.11%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 7.41%
Procedural Pain: 2 people, 7.41%
Nausea (feeling of having an urge to vomit): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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