Solu-medrol and Pradaxa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Solu-medrol (methylprednisolone sodium succinate) and Pradaxa (dabigatran etexilate mesylate). Common drug interactions include convulsion among females and hypertension among males.

The phase IV clinical study analyzes what interactions people have when they take Solu-medrol and Pradaxa. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Solu-medrol?

Solu-medrol has active ingredients of methylprednisolone sodium succinate. It is often used in multiple sclerosis. eHealthMe is studying from 39,410 Solu-medrol users. Check the latest studies of Solu-medrol.

What is Pradaxa?

Pradaxa has active ingredients of dabigatran etexilate mesylate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 86,906 Pradaxa users. Check the latest studies of Pradaxa.

On Jul, 12, 2026

38 people who take Solu-medrol and Pradaxa together, and have interactions are studied.

Solu-medrol and Pradaxa drug interactions.

What are the common drug interactions of Solu-Medrol and Pradaxa, by gender? *:

female:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Diarrhoea
Dizziness
Drug dependence
Drug ineffective
Dysphagia (a condition in which swallowing is difficult or painful)
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Feeling hot
Haemoglobin decreased

male:

Hypertension (high blood pressure)
Asthenia (weakness)
Haematocrit decreased
Haemoglobin decreased
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Intervertebral disc degeneration (spinal disc degeneration)
Intervertebral disc protrusion (spinal disc protrusion)
Lymphocyte count decreased
Mean cell haemoglobin concentration increased (more concentration of haemoglobin in a given volume of packed red blood cells)
Mean cell volume increased (more than normal average red blood cell volume)

What are the common drug interactions of Solu-Medrol and Pradaxa, by age (0-1 to 60+)? *:

0-1:

Acute respiratory failure
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Drug dependence
Pulmonary alveolar haemorrhage (acute bleeding)
Renal failure acute (rapid kidney dysfunction)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chest discomfort
Dyspnoea (difficult or laboured respiration)
Pain in extremity
Pulmonary embolism (blockage of the main artery of the lung)
Throat irritation
Thrombosis (formation of a blood clot inside a blood vessel)

50-59:

Tremor (trembling or shaking movements in one or more parts of your body)
Visual impairment
Arthropathy
Asthenia (weakness)
Brachial plexopathy (pain, decreased movement, or decreased sensation in the arm and shoulder due to a nerve problem)
Cellulitis (infection under the skin)
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Cervical spinal stenosis (narrowing of the spinal canal in the neck)
Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)
Eosinophil count decreased

60+:

Hypertension (high blood pressure)
Hyperthermia (body temperature greatly above normal)
Addison's disease (addison's disease, a hormonal disorder disease)
Asthenia (weakness)
Blood pressure decreased
Blood pressure fluctuation
Body temperature fluctuation
Bradycardia (abnormally slow heart action)
Cardiac failure congestive
Endotracheal intubation complication

What are the existing conditions these people have? *

Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 7 people, 18.42%
Pain: 5 people, 13.16%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 4 people, 10.53%
Stress And Anxiety: 3 people, 7.89%
Depression: 3 people, 7.89%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 5.26%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 5.26%
Hypoglycemia (low blood sugar): 2 people, 5.26%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.26%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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