Soma and Divalproex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Soma (carisoprodol) and Divalproex (divalproex sodium). Common drug interactions include sacroiliitis among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Soma and Divalproex. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Soma?

Soma has active ingredients of carisoprodol. It is often used in muscle spasms. eHealthMe is studying from 17,137 Soma users. Check the latest studies of Soma.

What is Divalproex?

Divalproex has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 14,063 Divalproex users. Check the latest studies of Divalproex.

On Jul, 26, 2026

15 people who take Soma and Divalproex together, and have interactions are studied.

What are the common drug interactions of Soma and Divalproex, by gender? *:

female:

Sacroiliitis (an inflammation of the sacroiliac joint)
Scoliosis (a medical condition in which a person's spine is curved from side to side)
Skin discolouration (change of skin colour)
Social avoidant behaviour (avoiding social connection a personality disorder)
Stress
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
Substance-induced psychotic disorder
Tachyphrenia (abnormally rapid mental activity)
Ulcer
Urinary retention (the inability to completely or partially empty the bladder)

male:

Asthenia (weakness)
Hypoaesthesia (reduced sense of touch or sensation)
Cardiomegaly (increased size of heart than normal)
Drug dependence
Respiratory failure (inadequate gas exchange by the respiratory system)
Malaise (a feeling of general discomfort or uneasiness)
Protein urine present
Renal pain (kidney pain)
Weight decreased
Accident

What are the common drug interactions of Soma and Divalproex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Asthenia (weakness)
Hypoaesthesia (reduced sense of touch or sensation)
Migraine (headache)
Neck pain
Pain in extremity
Prostatitis (inflammation of the prostate gland)
Renal disorder (kidney disease)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Accidental death
Blood urine present

40-49:

Chronic kidney disease
Conjunctivitis (pink eye)
Ocular hyperaemia (an abnormally large amount of blood in eye)
Renal failure (kidney dysfunction)
Ulcer

50-59:

Agitation (state of anxiety or nervous excitement)
Anger
Anxiety
Aortic valve stenosis (narrowing of the aortic valve)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bradycardia (abnormally slow heart action)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Depression
Disturbance in attention
Dyspnoea (difficult or laboured respiration)

60+:

Dizziness
Abdominal pain
Emotional disorder
Euphoric mood (excessively happy but may become angry or irritable)
Fall
Fatigue (feeling of tiredness)
Loss of consciousness
Overdose
Pain in extremity
Urinary incontinence (inability to control the flow of urine and involuntary urination)

What are the existing conditions these people have? *

Pain: 8 people, 53.33%
High Blood Pressure: 3 people, 20.00%
Vitamin D Decreased: 1 person, 6.67%
Inflammation: 1 person, 6.67%
Back Disorder: 1 person, 6.67%
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 1 person, 6.67%
Diabetes: 1 person, 6.67%
Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 6.67%
Fungal Infection: 1 person, 6.67%
Gastric Ulcer (stomach ulcer): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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