Somavert and Melatonin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Somavert (pegvisomant) and Melatonin (melatonin). Common drug interactions include bone pain among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Somavert and Melatonin. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Somavert?

Somavert has active ingredients of pegvisomant. eHealthMe is studying from 5,774 Somavert users. Check the latest studies of Somavert.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,212 Melatonin users. Check the latest studies of Melatonin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 14, 2026

57 people who take Somavert and Melatonin together, and have interactions are studied.

Somavert and Melatonin drug interactions.

What are the common drug interactions of Somavert and Melatonin, by gender? *:

female:

Bone pain
Drug hypersensitivity
Epistaxis (bleed from the nose)
Haemorrhage (bleeding)
Headache (pain in head)
Heart rate decreased
Hypotension (abnormally low blood pressure)
Injection site swelling
Limb discomfort (discomfort in leg)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

male:

Diarrhoea
Blood growth hormone increased
Eye movement disorder
Fall
Foot deformity (functional disability of foot)
Gait disturbance
Gastric hypomotility (less movement of stomach)
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
Influenza
Infrequent bowel movements

What are the common drug interactions of Somavert and Melatonin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Injection site pain
Hepatic enzyme increased
Growth hormone-producing pituitary tumour
Breath odour
Hepatotoxicity (chemical-driven liver damage)
Abdominal pain
Agitation (state of anxiety or nervous excitement)
Blood growth hormone increased
Brain injury
Chest pain

20-29:

Abdominal pain upper
Blood growth hormone increased
Gastric disorder (disease of stomach)
Malaise (a feeling of general discomfort or uneasiness)
Peripheral swelling
Rash
Abdominal discomfort
Abdominal distension
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Confusional state

30-39:

Asthenia (weakness)
Blood glucose increased
Dry eye (lack of adequate tears)
Dry mouth
Eye pain
Fatigue (feeling of tiredness)
Feeding disorder (when children refuse to eat certain food groups)
Headache (pain in head)
Pain
Photophobia (extreme sensitivity to light)

40-49:

Alanine aminotransferase increased
Constipation

50-59:

Peripheral swelling
Somnolence (a state of near-sleep, a strong desire for sleep)
Muscle spasms (muscle contraction)
Abdominal pain upper
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Abdominal distension
Abdominal pain
Anxiety
Back pain
Blood pressure increased

60+:

Injection site mass
Axillary mass
Injection site bruising
Injection site pain
Insulin-like growth factor decreased

What are the existing conditions these people have? *

Pituitary Tumor: 39 people, 68.42%
Growth Hormone-Producing Pituitary Tumor: 38 people, 66.67%
Constipation: 34 people, 59.65%
Tremor (trembling or shaking movements in one or more parts of your body): 30 people, 52.63%
Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 16 people, 28.07%
Adrenal Insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids): 4 people, 7.02%
Neuroendocrine Carcinoma Metastatic (cancer tumour that arise from cells of the endocrine (hormonal) and nervous systems and spreads to other part): 3 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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