Somavert and Pregabalin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Somavert (pegvisomant) and Pregabalin (pregabalin). Common drug interactions include hepatic cirrhosis among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Somavert and Pregabalin. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Somavert?

Somavert has active ingredients of pegvisomant. eHealthMe is studying from 5,774 Somavert users. Check the latest studies of Somavert.

What is Pregabalin?

Pregabalin has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 74,070 Pregabalin users. Check the latest studies of Pregabalin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 19, 2026

22 people who take Somavert and Pregabalin together, and have interactions are studied.

Somavert and Pregabalin drug interactions.

What are the common drug interactions of Somavert and Pregabalin, by gender? *:

female:

  1. Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
  2. Renal disorder (kidney disease)
  3. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
  4. Weight decreased
  5. Pituitary tumour benign
  6. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  7. Disease progression
  8. Fatigue (feeling of tiredness)
  9. Pituitary tumour
  10. Decreased appetite

male:

  1. Arthralgia (joint pain)
  2. Blood pressure systolic increased
  3. Pneumonia
  4. Poor quality sleep
  5. Rhinitis allergic (inflammation of the nasal airways due to allergy)
  6. Somnolence (a state of near-sleep, a strong desire for sleep)
  7. Weight decreased
  8. Arrhythmia (irregular heartbeat)
  9. Incontinence (lack of moderation or self-control)
  10. Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)

What are the common drug interactions of Somavert and Pregabalin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Pituitary tumour benign

50-59:

  1. Weight decreased
  2. Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
  3. Renal disorder (kidney disease)
  4. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
  5. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  6. Fatigue (feeling of tiredness)
  7. Disease progression
  8. Pituitary tumour
  9. Dry mouth
  10. Dyspepsia (indigestion)

60+:

  1. Arthralgia (joint pain)
  2. Blood pressure systolic increased
  3. Lethargy (tiredness)
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Pneumonia
  6. Bradycardia (abnormally slow heart action)
  7. Fall
  8. Gait disturbance
  9. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  10. Arrhythmia (irregular heartbeat)

What are the existing conditions these people have? *

  1. Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 14 people, 63.64%
  2. Diabetes: 6 people, 27.27%
  3. Apnea (temporary absence or cessation of breathing): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Somavert and Pregabalin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Somavert:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pregabalin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Somavert and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pregabalin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on pegvisomant and pregabalin (the active ingredients of Somavert and Pregabalin, respectively), and Somavert and Pregabalin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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