Cardene and Bradycardia - a phase IV clinical study of FDA data

Summary:

Bradycardia is reported as a side effect among people who take Cardene (nicardipine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Mellaril, and have Analgesic effect.

The phase IV clinical study analyzes which people have Bradycardia when taking Cardene. It is created by eHealthMe based on reports of 723 people who have side effects when taking Cardene from the FDA, and is updated regularly.

What is Cardene?

Cardene has active ingredients of nicardipine hydrochloride. eHealthMe is studying from 729 Cardene users. Check the latest studies of Cardene.

What is Bradycardia?

Bradycardia (abnormally slow heart action) is found to be associated with 1,917 drugs and 3,118 conditions by eHealthMe. Check the latest studies of Bradycardia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 19, 2026

723 people reported to have side effects when taking Cardene.
Among them, 15 people (2.07%) have Bradycardia.

Among these 15 people:

How long have people been on Cardene when they have Bradycardia? *

What is the gender of people who have Bradycardia when taking Cardene? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Bradycardia when taking Cardene? *

What are other drugs people take besides Cardene? *

What are other side effects people have besides Bradycardia? *

Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 4 people, 26.67%
Hyperkalemia (damage to or disease of the kidney): 4 people, 26.67%
Hypotension (abnormally low blood pressure): 4 people, 26.67%
Electrocardiogram Qt Prolonged: 3 people, 20.00%
Ventricular Extrasystoles (premature cardiac contraction): 3 people, 20.00%
Chest Pain: 3 people, 20.00%
Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 3 people, 20.00%
Blood Creatine Phosphokinase Increased: 2 people, 13.33%
Nodal Arrhythmia (an irregular heart beat originating from within the atrioventricular node): 2 people, 13.33%
Loss Of Consciousness: 2 people, 13.33%

What are the existing conditions these people have? *

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 6.67%
Ischaemic Stroke (stroke; caused by an interruption in the flow of blood to the brain): 1 person, 6.67%
High Blood Pressure: 1 person, 6.67%
Analgesic Effect: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Cardene and have Bradycardia?

- Check whether Bradycardia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cardene:

Cardene (729 reports)

Bradycardia treatments and more:

Bradycardia (61,180 reports)

Browse all side effects of Cardene:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bradycardia:

Bradycardia (1,917 drugs)

Browse all the conditions that are associated with Bradycardia:

Bradycardia (3,118 conditions)

Related publications that referenced our studies

Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
Oflaz MB, Kucukdurmaz Z, Guven AS, Karapinar H, Kaya A, Sancakdar E, Deveci K, Gul I, Erdem A, Cevit O, Icagasioglu FD, "Bradycardia seen in children with Crimean-Congo hemorrhagic fever", Vector-Borne and Zoonotic Diseases, 2013 Nov .
Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
Oflaz MB, Kucukdurmaz Z, Guven AS, Karapinar H, Kaya A, Sancakdar E, Deveci K, Gul I, Erdem A, Cevit O, Icagasioglu FD, "Bradycardia seen in children with Crimean-Congo hemorrhagic fever", Vector-Borne and Zoonotic Diseases, 2013 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on nicardipine hydrochloride (the active ingredients of Cardene) and Cardene (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.