Sotalol hydrochloride and Tikosyn drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sotalol hydrochloride (sotalol hydrochloride) and Tikosyn (dofetilide). Common drug interactions include drug ineffective among females and myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Sotalol hydrochloride and Tikosyn. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Sotalol hydrochloride?

Sotalol hydrochloride has active ingredients of sotalol hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 3,643 Sotalol hydrochloride users. Check the latest studies of Sotalol hydrochloride.

What is Tikosyn?

Tikosyn has active ingredients of dofetilide. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 12,202 Tikosyn users. Check the latest studies of Tikosyn.

On Jul, 28, 2026

30 people who take Sotalol hydrochloride and Tikosyn together, and have interactions are studied.

Sotalol hydrochloride and Tikosyn drug interactions.

What are the common drug interactions of Sotalol Hydrochloride and Tikosyn, by gender? *:

female:

Drug ineffective
Drug hypersensitivity
Fatigue (feeling of tiredness)
Fluid retention (an abnormal accumulation of fluid in the blood)
Hypersensitivity
Nausea (feeling of having an urge to vomit)
Extrasystoles
Heart rate decreased
Blood pressure decreased
Blood pressure increased

male:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Pericardial haemorrhage (bleeding into the heart)
Cough
Drug ineffective
Dry mouth
Dysphagia (a condition in which swallowing is difficult or painful)
Ear discomfort
Hearing impaired
Influenza like illness

What are the common drug interactions of Sotalol Hydrochloride and Tikosyn, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Arrhythmia supraventricular (irregular heartbeat supraventricular origin)
Cardiac failure congestive
Cardioversion
Continuous positive airway pressure
Dizziness
Exercise tolerance decreased
Fatigue (feeling of tiredness)
Heart rate irregular
Hyperlipidaemia (presence of excess lipids in the blood)
Hypertension (high blood pressure)

60+:

Coronary artery thrombosis (clot formation in coronary artery)
Dizziness
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Cough
Dry mouth
Dysphagia (a condition in which swallowing is difficult or painful)
Ear discomfort
Extrasystoles
Hearing impaired
Heart rate decreased

What are the existing conditions these people have? *

Idiopathic Pulmonary Fibrosis (chronic lung disease): 8 people, 26.67%
Heart Attack: 8 people, 26.67%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 10.00%
Pain: 3 people, 10.00%
Chest Pain: 3 people, 10.00%
High Blood Cholesterol: 2 people, 6.67%
Constipation: 2 people, 6.67%
Arrhythmias (irregular heartbeat): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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