Sovaldi and Lexapro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sovaldi (sofosbuvir) and Lexapro (escitalopram oxalate). Common drug interactions include fatigue among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Sovaldi and Lexapro. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Sovaldi?

Sovaldi has active ingredients of sofosbuvir. eHealthMe is studying from 12,697 Sovaldi users. Check the latest studies of Sovaldi.

What is Lexapro?

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.

On Aug, 12, 2026

41 people who take Sovaldi and Lexapro together, and have interactions are studied.

What are the common drug interactions of Sovaldi and Lexapro, by gender? *:

female:

Fatigue (feeling of tiredness)
Headache (pain in head)
Death
Nausea (feeling of having an urge to vomit)
Pain
Influenza like illness
Anaemia (lack of blood)
Arthralgia (joint pain)
Energy increased
Influenza

male:

Fatigue (feeling of tiredness)
Hepatitis c
Blood cholesterol increased
Compulsive sexual behaviour (unable to manage his/her sexual behaviour)
Compulsive shopping
Decreased appetite
Eating disorder
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hyperhidrosis (abnormally increased sweating)
Influenza like illness

What are the common drug interactions of Sovaldi and Lexapro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Pain
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Asthenia (weakness)
Fatigue (feeling of tiredness)
Hyperhidrosis (abnormally increased sweating)
Pyrexia (fever)
Vomiting

30-39:

Eyelid ptosis (falling of the upper or lower eyelid)

40-49:

n/a

50-59:

Fatigue (feeling of tiredness)
Platelet count increased
Influenza like illness
Anaemia (lack of blood)
Asthenia (weakness)
Bacterial infection
Contusion (a type of hematoma of tissue in which capillaries)
Energy increased
Glossitis (infection of tongue with soreness)
Headache (pain in head)

60+:

Death
Fatigue (feeling of tiredness)
Feeling cold
Feeling hot
Hepatitis c
Hypoaesthesia (reduced sense of touch or sensation)
Influenza like illness
Lacrimation increased
Neuropathy peripheral (surface nerve damage)
Oral mucosal blistering (mouth ulcer)

What are the existing conditions these people have? *

Hepatitis C: 30 people, 73.17%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 9.76%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 9.76%
Diabetes: 4 people, 9.76%
Pain: 3 people, 7.32%
Oesophagitis (inflammation of oesophagus): 3 people, 7.32%
Neuralgia (pain in one or more nerves): 3 people, 7.32%
Hepatic Artery Thrombosis (formation of a blood clot inside a hepatic artery): 3 people, 7.32%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

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