Spiriva respimat and Cosopt drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Spiriva respimat (tiotropium bromide) and Cosopt (dorzolamide hydrochloride; timolol maleate). Common drug interactions include alopecia among females and myocarditis among males.

The phase IV clinical study analyzes what interactions people have when they take Spiriva respimat and Cosopt. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Spiriva respimat?

Spiriva respimat has active ingredients of tiotropium bromide. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 9,788 Spiriva respimat users. Check the latest studies of Spiriva respimat.

What is Cosopt?

Cosopt has active ingredients of dorzolamide hydrochloride; timolol maleate. It is often used in glaucoma. eHealthMe is studying from 9,029 Cosopt users. Check the latest studies of Cosopt.



On Jul, 17, 2026

11 people who take Spiriva respimat and Cosopt together, and have interactions are studied.

Spiriva respimat and Cosopt drug interactions.

What are the common drug interactions of Spiriva Respimat and Cosopt, by gender? *:

female:

  1. Alopecia (absence of hair from areas of the body)
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Arthralgia (joint pain)
  4. Asthenia (weakness)
  5. Chest discomfort
  6. Contusion (a type of hematoma of tissue in which capillaries)
  7. Depression
  8. Diarrhoea
  9. Diplopia (double vision)
  10. Disturbance in attention

male:

  1. Myocarditis (inflammation of heart muscle myocardium)
  2. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  3. Eye disorder
  4. Eye pain
  5. Eye swelling
  6. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  7. Hidradenitis (chronic disease of a type of sweat gland)
  8. Ocular hyperaemia (an abnormally large amount of blood in eye)
  9. Rash
  10. Wound infection

What are the common drug interactions of Spiriva Respimat and Cosopt, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Myocarditis (inflammation of heart muscle myocardium)
  2. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  3. Contusion (a type of hematoma of tissue in which capillaries)
  4. Depression
  5. Diarrhoea
  6. Diplopia (double vision)
  7. Disturbance in attention
  8. Dizziness
  9. Dry mouth
  10. Dysgeusia (disorder of the sense of taste)

What are the existing conditions these people have? *

  1. Lung Cancer - Non-Small Cell (lung cancer): 5 people, 45.45%
  2. Nausea (feeling of having an urge to vomit): 4 people, 36.36%
  3. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 27.27%
  4. High Blood Cholesterol: 3 people, 27.27%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 18.18%
  6. Pain: 2 people, 18.18%
  7. Constipation: 2 people, 18.18%
  8. Iron Deficiency: 2 people, 18.18%
  9. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 18.18%
  10. Wound Infection: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Spiriva respimat and Cosopt?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Spiriva respimat and Cosopt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Spiriva respimat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cosopt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Spiriva respimat and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cosopt and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tiotropium bromide and dorzolamide hydrochloride; timolol maleate (the active ingredients of Spiriva respimat and Cosopt, respectively), and Spiriva respimat and Cosopt (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: