Spiriva and Lubiprostone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Spiriva (tiotropium bromide monohydrate) and Lubiprostone (lubiprostone). Common drug interactions include dizziness among females and neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Spiriva and Lubiprostone. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Spiriva?

Spiriva has active ingredients of tiotropium bromide monohydrate. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 156,666 Spiriva users. Check the latest studies of Spiriva.

What is Lubiprostone?

Lubiprostone has active ingredients of lubiprostone. eHealthMe is studying from 957 Lubiprostone users. Check the latest studies of Lubiprostone.

On Jul, 05, 2026

11 people who take Spiriva and Lubiprostone together, and have interactions are studied.

Spiriva and Lubiprostone drug interactions.

What are the common drug interactions of Spiriva and Lubiprostone, by gender? *:

female:

Dizziness
Nausea (feeling of having an urge to vomit)
Weight decreased
Abdominal discomfort
Abdominal pain
Anaemia (lack of blood)
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Arthralgia (joint pain)
Blood creatine increased
Chest discomfort

male:

Neutropenia (an abnormally low number of neutrophils)
Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
Constipation
Diarrhoea
Dizziness
Drug effect decreased
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Head discomfort
Lung disorder (lung disease)

What are the common drug interactions of Spiriva and Lubiprostone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease

50-59:

Neutropenia (an abnormally low number of neutrophils)
Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Neoplasm malignant (cancer tumour)

60+:

Dizziness
Nausea (feeling of having an urge to vomit)
Arthralgia (joint pain)
Asthenia (weakness)
Blood creatine increased
Chest discomfort
Constipation
Contusion (a type of hematoma of tissue in which capillaries)
Cough
Decreased appetite

What are the existing conditions these people have? *

Constipation: 4 people, 36.36%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 3 people, 27.27%
Fever: 3 people, 27.27%
Pain: 3 people, 27.27%
High Blood Pressure: 3 people, 27.27%
Stress And Anxiety: 3 people, 27.27%
High Blood Cholesterol: 3 people, 27.27%
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur): 3 people, 27.27%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 2 people, 18.18%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Spiriva and Lubiprostone?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously