Spironolactone and Doptelet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Spironolactone (spironolactone) and Doptelet (avatrombopag maleate). Common drug interactions include nausea among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Spironolactone and Doptelet. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Spironolactone?

Spironolactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 122,947 Spironolactone users. Check the latest studies of Spironolactone.

What is Doptelet?

Doptelet has active ingredients of avatrombopag maleate. eHealthMe is studying from 1,389 Doptelet users. Check the latest studies of Doptelet.

On Jul, 05, 2026

21 people who take Spironolactone and Doptelet together, and have interactions are studied.

Spironolactone and Doptelet drug interactions.

What are the common drug interactions of Spironolactone and Doptelet, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Vomiting
Adverse drug reaction
Arthralgia (joint pain)
Fatigue (feeling of tiredness)
Feeling of body temperature change
Peripheral swelling
Platelet count decreased
Pyrexia (fever)
Influenza like illness

male:

Fatigue (feeling of tiredness)
Abdominal discomfort
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hypersomnia (excessive daytime sleepiness (eds))
Liver disorder (liver diseases)
Varices oesophageal (enlarged and swollen veins at the bottom of the oesophagus, near the stomach)
Abdominal pain
Blood bilirubin increased
Decreased appetite

What are the common drug interactions of Spironolactone and Doptelet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Breath odour
Diarrhoea
Drug ineffective
Fatigue (feeling of tiredness)
Flatulence (flatus expelled through the anus)
Hypersomnia (excessive daytime sleepiness (eds))

60+:

Nausea (feeling of having an urge to vomit)
Vomiting
Skin exfoliation (removal of the oldest dead skin cells)
Urinary tract infection
Asthenia (weakness)
Blood disorder
Chronic kidney disease
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Liver disorder (liver diseases)

What are the existing conditions these people have? *

Thrombocytopenia (decrease of platelets in blood): 9 people, 42.86%
Sleep Disorder: 2 people, 9.52%
Liver Disorder (liver diseases): 2 people, 9.52%
Hepatitis Viral: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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