Spironolactone and Maxair drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Spironolactone (spironolactone) and Maxair (pirbuterol acetate). Common drug interactions include autonomic neuropathy among females and dysgeusia among males.

The phase IV clinical study analyzes what interactions people have when they take Spironolactone and Maxair. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Spironolactone?

Spironolactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 122,947 Spironolactone users. Check the latest studies of Spironolactone.

What is Maxair?

Maxair has active ingredients of pirbuterol acetate. It is often used in asthma. eHealthMe is studying from 2,903 Maxair users. Check the latest studies of Maxair.



On Jul, 10, 2026

37 people who take Spironolactone and Maxair together, and have interactions are studied.

Spironolactone and Maxair drug interactions.

What are the common drug interactions of Spironolactone and Maxair, by gender? *:

female:

  1. Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
  2. Bladder spasm
  3. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  4. Exostosis (formation of new bone on the surface of a bone)
  5. Fatigue (feeling of tiredness)
  6. Fibromyalgia (a long-term condition which causes pain all over the body)
  7. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  8. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  9. Migraine (headache)
  10. Nerve injury

male:

  1. Dysgeusia (disorder of the sense of taste)
  2. Death
  3. Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
  4. Tremor (trembling or shaking movements in one or more parts of your body)

What are the common drug interactions of Spironolactone and Maxair, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

30-39:

n/a

40-49:

  1. Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
  2. Bladder spasm
  3. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  4. Exostosis (formation of new bone on the surface of a bone)
  5. Fatigue (feeling of tiredness)
  6. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  7. Pain
  8. Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
  9. Spinal column stenosis (narrowing of spinal column)
  10. Spinal cord injury

50-59:

  1. Urinary retention (the inability to completely or partially empty the bladder)
  2. Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
  3. Bladder spasm
  4. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  5. Exostosis (formation of new bone on the surface of a bone)
  6. Fatigue (feeling of tiredness)
  7. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  8. Spinal cord injury
  9. Tooth disorder (tooth disease)
  10. Vocal cord disorder

60+:

  1. Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
  2. Bone marrow depression (decreased ability or inability of the bone marrow to produce blood cells)
  3. Sinusitis (inflammation of sinus)
  4. Tremor (trembling or shaking movements in one or more parts of your body)
  5. White blood cell count decreased
  6. Bronchial obstruction (blockage of the breathing passages to the lungs)
  7. Cough
  8. Dyspnoea (difficult or laboured respiration)
  9. Haematocrit decreased
  10. Insulin-requiring type ii diabetes mellitus

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 18 people, 48.65%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 15 people, 40.54%
  3. Thrombosis (formation of a blood clot inside a blood vessel): 2 people, 5.41%
  4. Sleep Disorder: 2 people, 5.41%
  5. Pulmonary Embolism (blockage of the main artery of the lung): 2 people, 5.41%
  6. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 5.41%
  7. Joint Pain: 2 people, 5.41%
  8. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Spironolactone and Maxair:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Spironolactone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Maxair:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Spironolactone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Maxair and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on spironolactone and pirbuterol acetate (the active ingredients of Spironolactone and Maxair, respectively), and Spironolactone and Maxair (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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