Spironolactone and Prempro drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Spironolactone (spironolactone) and Prempro (estrogens, conjugated; medroxyprogesterone acetate). Common drug interactions include breast cancer among females.
The phase IV clinical study analyzes what interactions people have when they take Spironolactone and Prempro. It is created by eHealthMe based on reports of 130 people who take the same drugs from the FDA, and is updated regularly.
What is Spironolactone?
Spironolactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 122,947 Spironolactone users. Check the latest studies of Spironolactone.
What is Prempro?
Prempro has active ingredients of estrogens, conjugated; medroxyprogesterone acetate. It is often used in menopause. eHealthMe is studying from 42,950 Prempro users. Check the latest studies of Prempro.
130 people who take Spironolactone and Prempro together, and have interactions are studied.

What are the common drug interactions of Spironolactone and Prempro, by gender? *
What are the common drug interactions of Spironolactone and Prempro, by age (0-1 to 60+)? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Spironolactone and Prempro?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Spironolactone (122,947 reports)
- Prempro (42,950 reports)
Browse all drug interactions of Spironolactone and Prempro:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Spironolactone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Prempro:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Spironolactone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Prempro and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on spironolactone and estrogens, conjugated; medroxyprogesterone acetate (the active ingredients of Spironolactone and Prempro, respectively), and Spironolactone and Prempro (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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