Spironolactone and Slynd drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Spironolactone (spironolactone) and Slynd (drospirenone). Common drug interactions include fatigue among females.

The phase IV clinical study analyzes what interactions people have when they take Spironolactone and Slynd. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Spironolactone?

Spironolactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 122,947 Spironolactone users. Check the latest studies of Spironolactone.

What is Slynd?

Slynd has active ingredients of drospirenone. It is often used in birth control. eHealthMe is studying from 1,658 Slynd users. Check the latest studies of Slynd.

On Jul, 27, 2026

17 people who take Spironolactone and Slynd together, and have interactions are studied.

Spironolactone and Slynd drug interactions.

What are the common drug interactions of Spironolactone and Slynd, by gender? *:

female:

Fatigue (feeling of tiredness)
Headache (pain in head)
Fibromyalgia (a long-term condition which causes pain all over the body)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Pneumonia
Thyroid cancer
Urinary tract infection
Allergy to metals
Blood potassium increased
Blood triglycerides decreased

male:

n/a

What are the common drug interactions of Spironolactone and Slynd, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Surgery

30-39:

Fatigue (feeling of tiredness)
Anxiety
Fibromyalgia (a long-term condition which causes pain all over the body)
Headache (pain in head)
Hypersensitivity
Inflammation
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Myalgia (muscle pain)
Sluggishness (lacking alertness)
Thyroid cancer

40-49:

Fatigue (feeling of tiredness)
Headache (pain in head)
Hypersensitivity
Inflammation
Influenza
Malaise (a feeling of general discomfort or uneasiness)
Myalgia (muscle pain)
Sinusitis (inflammation of sinus)
Sluggishness (lacking alertness)

50-59:

Death

60+:

n/a

What are the existing conditions these people have? *

Migraine (headache): 4 people, 23.53%
Stress And Anxiety: 3 people, 17.65%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 17.65%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 17.65%
Muscle Spasms (muscle contraction): 3 people, 17.65%
Dizziness: 3 people, 17.65%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 3 people, 17.65%
Acne Cystic (skin problems that cause pimples): 3 people, 17.65%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 11.76%
Lipodystrophy Acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired): 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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