Sprintec and Fenofibrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sprintec (ethinyl estradiol; norgestimate) and Fenofibrate (fenofibrate). Common drug interactions include erythema among females and angina pectoris among males.

The phase IV clinical study analyzes what interactions people have when they take Sprintec and Fenofibrate. It is created by eHealthMe based on reports of 8 people who take the same drugs from the FDA, and is updated regularly.

What is Sprintec?

Sprintec has active ingredients of ethinyl estradiol; norgestimate. It is often used in birth control. eHealthMe is studying from 4,397 Sprintec users. Check the latest studies of Sprintec.

What is Fenofibrate?

Fenofibrate has active ingredients of fenofibrate. It is often used in high blood cholesterol. eHealthMe is studying from 40,456 Fenofibrate users. Check the latest studies of Fenofibrate.



On Mar, 24, 2026

8 people who take Sprintec and Fenofibrate together, and have interactions are studied.

Sprintec and Fenofibrate drug interactions.

What are the common drug interactions of Sprintec and Fenofibrate, by gender? *:

female:

  1. Erythema (redness of the skin)
  2. Injection site erythema (redness at injection site)
  3. Injection site pain
  4. Injection site pruritus (severe itching at injection site)
  5. Injection site swelling
  6. Rash
  7. Skin lesion
  8. Somnolence (a state of near-sleep, a strong desire for sleep)
  9. Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
  10. Blood glucose decreased

male:

  1. Angina pectoris (chest pain due to ischemia of the heart muscle)
  2. Back pain
  3. Hyperprolactinaemia (abnormally high levels of prolactin in the blood)
  4. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  5. Limb injury
  6. Osteopenia (a condition where bone mineral density is lower than normal)
  7. Osteoporosis (bones weak and more likely to break)
  8. Plasma cell myeloma (cancer that begins in plasma cells)
  9. Post-traumatic stress disorder
  10. Pulmonary embolism (blockage of the main artery of the lung)

What are the common drug interactions of Sprintec and Fenofibrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Blood glucose decreased
  2. Palpitations (feelings or sensations that your heart is pounding or racing)

30-39:

  1. Erythema (redness of the skin)
  2. Injection site erythema (redness at injection site)
  3. Injection site pain
  4. Injection site pruritus (severe itching at injection site)
  5. Injection site swelling
  6. Rash
  7. Skin lesion
  8. Somnolence (a state of near-sleep, a strong desire for sleep)
  9. Cough
  10. Ear pain

40-49:

n/a

50-59:

n/a

60+:

  1. Angina pectoris (chest pain due to ischemia of the heart muscle)
  2. Back pain
  3. Hyperprolactinaemia (abnormally high levels of prolactin in the blood)
  4. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  5. Limb injury
  6. Osteopenia (a condition where bone mineral density is lower than normal)
  7. Osteoporosis (bones weak and more likely to break)
  8. Plasma cell myeloma (cancer that begins in plasma cells)
  9. Post-traumatic stress disorder
  10. Pulmonary embolism (blockage of the main artery of the lung)

* Approximation only. Some reports may have incomplete information.

Do you take Sprintec and Fenofibrate?

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Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Sprintec and Fenofibrate:

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Browse all side effects of Sprintec:

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Browse all side effects of Fenofibrate:

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Browse all interactions between Sprintec and drugs from A to Z:

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Browse all interactions between Fenofibrate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ethinyl estradiol; norgestimate and fenofibrate (the active ingredients of Sprintec and Fenofibrate, respectively), and Sprintec and Fenofibrate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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