Sprycel and Glucophage drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sprycel (dasatinib) and Glucophage (metformin hydrochloride). Common drug interactions include general physical health deterioration among females and pleural effusion among males.

The phase IV clinical study analyzes what interactions people have when they take Sprycel and Glucophage. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Sprycel?

Sprycel has active ingredients of dasatinib. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 29,788 Sprycel users. Check the latest studies of Sprycel.

What is Glucophage?

Glucophage has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 60,851 Glucophage users. Check the latest studies of Glucophage.

On Jul, 19, 2026

26 people who take Sprycel and Glucophage together, and have interactions are studied.

Sprycel and Glucophage drug interactions.

What are the common drug interactions of Sprycel and Glucophage, by gender? *:

female:

General physical health deterioration (weak health status)
Hepatitis acute
Nausea (feeling of having an urge to vomit)
Haematemesis (vomiting of blood)
Costochondritis (chest wall pain)
Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)
Pleurisy (inflammation of the pleurae, which causes pain when breathing)
Red blood cell count decreased
Abdominal discomfort
Adverse event

male:

Pleural effusion (water on the lungs)
Renal cancer (cancer of kidney)
Angiosarcoma metastatic (cancer of endothelial-type cells that line vessel walls-metastatic)
Arthralgia (joint pain)
Asthenia (weakness)
Back pain
Blood bilirubin increased
Blood iron increased
Bone marrow failure
Bone pain

What are the common drug interactions of Sprycel and Glucophage, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anaemia (lack of blood)
Blood glucose increased
Decreased appetite
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Gastrointestinal mucosal disorder (disorder of gastrointestinal lining mucous membranes)
Generalised oedema (swelling all over the body)
Malignant neoplasm progression (cancer tumour came back)
Neuropathy peripheral (surface nerve damage)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Platelet count decreased

40-49:

Costochondritis (chest wall pain)
Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)
Pleurisy (inflammation of the pleurae, which causes pain when breathing)
Red blood cell count decreased
Abdominal discomfort

50-59:

Cardiac disorder
Fatigue (feeling of tiredness)
Hypertension (high blood pressure)
Nausea (feeling of having an urge to vomit)
Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)

60+:

General physical health deterioration (weak health status)
Hepatitis acute
Anaemia (lack of blood)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Angiosarcoma metastatic (cancer of endothelial-type cells that line vessel walls-metastatic)
Arthralgia (joint pain)
Back pain
Blood bilirubin increased
Blood iron increased
Bone marrow failure

What are the existing conditions these people have? *

Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 14 people, 53.85%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 10 people, 38.46%
Type 2 Diabetes: 2 people, 7.69%
Stress And Anxiety: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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