Stelara and Paxil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Stelara (ustekinumab) and Paxil (paroxetine hydrochloride). Common drug interactions include crying among females and c-reactive protein increased among males.

The phase IV clinical study analyzes what interactions people have when they take Stelara and Paxil. It is created by eHealthMe based on reports of 85 people who take the same drugs from the FDA, and is updated regularly.

What is Stelara?

Stelara has active ingredients of ustekinumab. It is often used in psoriasis. eHealthMe is studying from 96,053 Stelara users. Check the latest studies of Stelara.

What is Paxil?

Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 92,546 Paxil users. Check the latest studies of Paxil.



On Jul, 18, 2026

85 people who take Stelara and Paxil together, and have interactions are studied.

Stelara and Paxil drug interactions.

What are the common drug interactions of Stelara and Paxil, by gender? *:

female:

  1. Crying
  2. Death
  3. Dehydration (dryness resulting from the removal of water)
  4. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  5. Drug hypersensitivity
  6. Eye discharge
  7. Fall
  8. Gastric ulcer (stomach ulcer)
  9. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  10. Head discomfort

male:

  1. C-reactive protein increased
  2. Diarrhoea
  3. Abdominal abscess (collection of pus in abdomen)
  4. Hyperkalaemia (damage to or disease of the kidney)
  5. Renal impairment (severely reduced kidney function)
  6. Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
  7. Bacterial infection
  8. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  9. Graft infection (infection of graft site)
  10. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

What are the common drug interactions of Stelara and Paxil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Abnormal loss of weight
  2. Decreased appetite
  3. Headache (pain in head)
  4. Nausea (feeling of having an urge to vomit)
  5. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
  6. Small intestinal perforation (hole in small intestine)

30-39:

  1. Eating disorder
  2. Gastric ulcer (stomach ulcer)
  3. Urinary tract infection
  4. Vomiting

40-49:

  1. Vision blurred
  2. Weight decreased
  3. C-reactive protein increased
  4. Diarrhoea
  5. Headache (pain in head)
  6. Hepatic enzyme increased
  7. Pyrexia (fever)
  8. White blood cell count increased
  9. Ascites (accumulation of fluid in the abdominal cavity)
  10. Hepatic cyst

50-59:

  1. Arthralgia (joint pain)
  2. Fatigue (feeling of tiredness)
  3. Chills (felling of cold)
  4. Decreased appetite
  5. Headache (pain in head)
  6. Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
  7. Myalgia (muscle pain)
  8. Pulmonary embolism (blockage of the main artery of the lung)
  9. Pyrexia (fever)
  10. Thrombosis (formation of a blood clot inside a blood vessel)

60+:

  1. Blood glucose increased
  2. Blood pressure increased
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Latent tuberculosis (hidden tuberculosis)
  5. Pneumonia
  6. Weight increased
  7. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  8. Dysphonia (speech disorder attributable to a disorder of phonation)
  9. Fatigue (feeling of tiredness)
  10. Incontinence (lack of moderation or self-control)

What are the existing conditions these people have? *

  1. Stress And Anxiety: 14 people, 16.47%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 14 people, 16.47%
  3. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 12 people, 14.12%
  4. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 8.24%
  5. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 8.24%
  6. High Blood Pressure: 5 people, 5.88%
  7. High Blood Cholesterol: 5 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Stelara and Paxil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Stelara:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Paxil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Stelara and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Paxil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ustekinumab and paroxetine hydrochloride (the active ingredients of Stelara and Paxil, respectively), and Stelara and Paxil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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