Stelara and Repatha drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Stelara (ustekinumab) and Repatha (evolocumab). Common drug interactions include arthritis among females and hospitalisation among males.

The phase IV clinical study analyzes what interactions people have when they take Stelara and Repatha. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Stelara?

Stelara has active ingredients of ustekinumab. It is often used in psoriasis. eHealthMe is studying from 96,053 Stelara users. Check the latest studies of Stelara.

What is Repatha?

Repatha has active ingredients of evolocumab. It is often used in high blood cholesterol. eHealthMe is studying from 156,256 Repatha users. Check the latest studies of Repatha.

On Jul, 09, 2026

19 people who take Stelara and Repatha together, and have interactions are studied.

What are the common drug interactions of Stelara and Repatha, by gender? *:

female:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Mobility decreased (ability to move is reduced)
Sensitivity of teeth
Malaise (a feeling of general discomfort or uneasiness)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
Rhinorrhoea (watery mucus discharge from the nose)
Back pain
Alopecia (absence of hair from areas of the body)

male:

Hospitalisation
Arthralgia (joint pain)
Coronavirus test positive
Drug ineffective
Knee arthroplasty
Pneumonia
Urticaria (rash of round, red welts on the skin that itch intensely)
Weight increased

What are the common drug interactions of Stelara and Repatha, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Rhinorrhoea (watery mucus discharge from the nose)
Malaise (a feeling of general discomfort or uneasiness)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)

40-49:

n/a

50-59:

Back pain
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Mobility decreased (ability to move is reduced)
Pneumonia

60+:

Arthralgia (joint pain)
Hospitalisation
Knee arthroplasty

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 6 people, 31.58%
Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 21.05%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 5.26%
Ischaemic Cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease): 1 person, 5.26%
Insomnia (sleeplessness): 1 person, 5.26%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.26%
Depression: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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