Stelara and Valacyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Stelara (ustekinumab) and Valacyclovir (valacyclovir hydrochloride). Common drug interactions include superinfection bacterial among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Stelara and Valacyclovir. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Stelara?

Stelara has active ingredients of ustekinumab. It is often used in psoriasis. eHealthMe is studying from 96,053 Stelara users. Check the latest studies of Stelara.

What is Valacyclovir?

Valacyclovir has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 42,108 Valacyclovir users. Check the latest studies of Valacyclovir.

eHealthMe: drug outcomes in the real world

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On Jul, 04, 2026

59 people who take Stelara and Valacyclovir together, and have interactions are studied.

Stelara and Valacyclovir drug interactions.

What are the common drug interactions of Stelara and Valacyclovir, by gender? *:

female:

Superinfection bacterial
Superinfection fungal
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Haemangioma (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs)
Premature baby
Intussusception
Respiratory syncytial virus infection (viral disease of respiratory system)
Sinusitis (inflammation of sinus)
Urinary tract infection
Gestational hypertension (elevated blood pressure during pregnancy)

male:

Abdominal pain
Intestinal haematoma (collection of blood, usually clotted, in intestine)
Intestinal resection
Jugular vein thrombosis (clot in jugular vein)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Nausea (feeling of having an urge to vomit)
Red blood cell macrocytes present
Subclavian vein thrombosis (abnormal condition in which a clot develops within the subclavian or axillary vein)
Wound infection
Abdominal pain lower

What are the common drug interactions of Stelara and Valacyclovir, by age (0-1 to 60+)? *:

0-1:

Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Haemangioma (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs)
Premature baby
Intussusception
Respiratory syncytial virus infection (viral disease of respiratory system)

2-9:

n/a

10-19:

Intestinal haematoma (collection of blood, usually clotted, in intestine)
Abdominal pain
Pyrexia (fever)

20-29:

Gestational hypertension (elevated blood pressure during pregnancy)
Premature labour
Sinusitis (inflammation of sinus)
Urinary tract infection
Anal abscess
Postoperative wound infection

30-39:

Decreased interest
Depressed mood
Depression
Gestational hypertension (elevated blood pressure during pregnancy)
Premature labour
Sinusitis (inflammation of sinus)
Urinary tract infection
Abdominal pain
Abdominal symptom
Gastrointestinal disorder (functional problems of gastrointestinal tract)

40-49:

Injection site erythema (redness at injection site)
Injection site swelling
Injection site urticaria (rash of round, red welts on the skin at injection site)
Injection site vesicles (fluid- or air-filled cavity or sac at injection site)
Injection site warmth
Neuralgia (pain in one or more nerves)
Precancerous skin lesion
Proctitis ulcerative (inflammation of the rectum and anus ulcerative)
Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin)
Tongue discolouration (colour change of tongue)

50-59:

Optic nerve injury
Abdominal hernia
Abdominal pain upper
Dehydration (dryness resulting from the removal of water)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Hospitalisation

60+:

Abdominal pain
Neoplasm malignant (cancer tumour)
Lung neoplasm malignant (cancer tumour of lung)
Nasopharyngitis (inflammation of the nasopharynx)
Urinary tract infection
Colitis (inflammation of colon)
Drug ineffective
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Groin pain
Hepatic enzyme increased

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 19 people, 32.20%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 10 people, 16.95%
Herpes Virus Infection: 8 people, 13.56%
Sleep Disorder: 8 people, 13.56%
Spondyloarthropathy (any joint disease of the vertebral column): 6 people, 10.17%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 6 people, 10.17%
Urinary Tract Infection: 5 people, 8.47%
Sinusitis (inflammation of sinus): 5 people, 8.47%
Multiple Allergies (allergy to multiple agents): 5 people, 8.47%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 6.78%

* Approximation only. Some reports may have incomplete information.

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