Stelazine and Ativan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Stelazine (trifluoperazine hydrochloride) and Ativan (lorazepam). Common drug interactions include bladder disorder among females and diabetes mellitus among males.

The phase IV clinical study analyzes what interactions people have when they take Stelazine and Ativan. It is created by eHealthMe based on reports of 81 people who take the same drugs from the FDA, and is updated regularly.

What is Stelazine?

Stelazine has active ingredients of trifluoperazine hydrochloride. It is often used in schizophrenia. eHealthMe is studying from 1,311 Stelazine users. Check the latest studies of Stelazine.

What is Ativan?

Ativan has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 78,506 Ativan users. Check the latest studies of Ativan.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 15, 2026

81 people who take Stelazine and Ativan together, and have interactions are studied.

What are the common drug interactions of Stelazine and Ativan, by gender? *:

female:

Bladder disorder
Psychotic disorder
Suicide attempt
Weight increased
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Agitation (state of anxiety or nervous excitement)
Death
Dementia (madness)
Pneumonia
Renal disorder (kidney disease)

male:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hypertension (high blood pressure)
Chronic obstructive airways disease
Diabetes mellitus inadequate control
Ear pain
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Upper respiratory tract infection
Bipolar disorder (mood disorder)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

What are the common drug interactions of Stelazine and Ativan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Dystonia (abnormal muscle tone)

20-29:

Fatigue (feeling of tiredness)
Type 2 diabetes mellitus
Abdominal pain upper
Adverse drug reaction
Affective disorder (mental disorder)
Agitation (state of anxiety or nervous excitement)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Antisocial personality disorder
Asthenia (weakness)
Attention deficit/hyperactivity disorder

30-39:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Pancreatitis (inflammation of pancreas)
Type 2 diabetes mellitus
Schizoaffective disorder (a mental disorder characterized by disordered thought)
Blood cholesterol increased
Suicide attempt
Abdominal pain
Bipolar disorder (mood disorder)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

40-49:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Gallbladder disorder
Hypertension (high blood pressure)
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Diabetic coma
Hepatic enzyme increased
Hepatic steatosis (fatty liver disease)
Liver disorder (liver diseases)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Overdose

50-59:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Type 2 diabetes mellitus
Hyperglycaemia (high blood sugar)
Tardive dyskinesia (a disorder that involves involuntary movements)
Weight increased
Irritable bowel syndrome
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Diabetic foot infection
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Diabetic ulcer

60+:

Renal disorder (kidney disease)
Agitation (state of anxiety or nervous excitement)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Upper respiratory tract infection
Sepsis (a severe blood infection that can lead to organ failure and death)
Abdominal pain
Alopecia (absence of hair from areas of the body)
Balance disorder
Biliary fistula

What are the existing conditions these people have? *

Depression: 31 people, 38.27%
Sleep Disorder: 17 people, 20.99%
Pain: 15 people, 18.52%
Bipolar Disorder (mood disorder): 13 people, 16.05%
Psychotic Disorder: 8 people, 9.88%
Insomnia (sleeplessness): 6 people, 7.41%
Agitation (state of anxiety or nervous excitement): 6 people, 7.41%
Schizoaffective Disorder Bipolar Type (mental illness featuring schizophrenia and a mood disorder with mania): 5 people, 6.17%
High Blood Pressure: 5 people, 6.17%

* Approximation only. Some reports may have incomplete information.

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