Stiolto respimat and Advair hfa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Stiolto respimat (olodaterol hydrochloride; tiotropium bromide) and Advair hfa (fluticasone propionate; salmeterol xinafoate). Common drug interactions include paraesthesia among females and atrial fibrillation among males.

The phase IV clinical study analyzes what interactions people have when they take Stiolto respimat and Advair hfa. It is created by eHealthMe based on reports of 93 people who take the same drugs from the FDA, and is updated regularly.

What is Stiolto respimat?

Stiolto respimat has active ingredients of olodaterol hydrochloride; tiotropium bromide. eHealthMe is studying from 4,438 Stiolto respimat users. Check the latest studies of Stiolto respimat.

What is Advair hfa?

Advair hfa has active ingredients of fluticasone propionate; salmeterol xinafoate. It is often used in asthma. eHealthMe is studying from 69,790 Advair hfa users. Check the latest studies of Advair hfa.

On Jul, 12, 2026

93 people who take Stiolto respimat and Advair hfa together, and have interactions are studied.

Stiolto respimat and Advair hfa drug interactions.

What are the common drug interactions of Stiolto Respimat and Advair Hfa, by gender? *:

female:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Petechiae (a small red or purple spot caused by bleeding into the skin)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Rash erythematous (redness of the skin)
Skin induration (an abnormally hard spot or area on the skin)
Skin swelling
Dyspnoea (difficult or laboured respiration)
Hypersensitivity

male:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Drug ineffective
Lung disorder (lung disease)
Lung transplant
Nephrolithiasis (calculi in the kidneys)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Productive cough
Prostate infection
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

What are the common drug interactions of Stiolto Respimat and Advair Hfa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Fatigue (feeling of tiredness)

40-49:

n/a

50-59:

Drug hypersensitivity
Loss of consciousness
Malaise (a feeling of general discomfort or uneasiness)
Mass
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Nausea (feeling of having an urge to vomit)
Pneumonia
Sepsis (a severe blood infection that can lead to organ failure and death)
Swollen tongue (swelling of tongue)
Tooth infection

60+:

Dyspnoea (difficult or laboured respiration)
Heart rate increased
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
Oedema peripheral (superficial swelling)
Rash
Abdominal distension
Alopecia (absence of hair from areas of the body)
Bladder irritation

What are the existing conditions these people have? *

Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 26 people, 27.96%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 15 people, 16.13%
Immunodeficiency Common Variable: 13 people, 13.98%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 10.75%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 9.68%
Stress And Anxiety: 8 people, 8.60%
Rashes (redness): 6 people, 6.45%
Quit Smoking: 6 people, 6.45%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 6 people, 6.45%
Oropharyngitis Fungal (fungal infection of oropharynx): 6 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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