Welchol and Bumetanide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Welchol (colesevelam hydrochloride) and Bumetanide (bumetanide). Common drug interactions include small intestinal obstruction among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Welchol and Bumetanide. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Welchol?

Welchol has active ingredients of colesevelam hydrochloride. It is often used in high blood cholesterol. eHealthMe is studying from 11,309 Welchol users. Check the latest studies of Welchol.

What is Bumetanide?

Bumetanide has active ingredients of bumetanide. It is often used in fluid retention. eHealthMe is studying from 20,532 Bumetanide users. Check the latest studies of Bumetanide.

On Jul, 12, 2026

57 people who take Welchol and Bumetanide together, and have interactions are studied.

Welchol and Bumetanide drug interactions.

What are the common drug interactions of Welchol and Bumetanide, by gender? *:

female:

Small intestinal obstruction (blockage in small intestine)
Somnolence (a state of near-sleep, a strong desire for sleep)
Staphylococcal infection (an infection with staphylococcus bacteria)
Thoracic vertebral fracture
Thrombosis (formation of a blood clot inside a blood vessel)
Urinary tract infection
Vitamin d decreased
Chronic kidney disease
Renal failure (kidney dysfunction)
Dyspnoea (difficult or laboured respiration)

male:

Chronic kidney disease
Depression
Micturition frequency decreased (less frequency of urinate)
Somnolence (a state of near-sleep, a strong desire for sleep)
Swelling face
Weight increased
Adverse drug reaction
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood urine present
Cardiac failure

What are the common drug interactions of Welchol and Bumetanide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Renal failure (kidney dysfunction)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Mobility decreased (ability to move is reduced)

50-59:

Adverse drug reaction
Asthma
Blood urine present
Cardiac failure congestive
Chronic kidney disease
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Drug effect decreased
Drug ineffective
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Oedema peripheral (superficial swelling)
Pain in extremity
Restless legs syndrome (a powerful urge to move your legs)
Swelling face
Syncope (loss of consciousness with an inability to maintain postural tone)
Weight increased
Abdominal pain
Abscess limb (limb infection)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 22 people, 38.60%
High Blood Pressure: 22 people, 38.60%
Depression: 20 people, 35.09%
Pain: 17 people, 29.82%
Infection: 15 people, 26.32%
Nausea (feeling of having an urge to vomit): 14 people, 24.56%
Stress And Anxiety: 14 people, 24.56%
Irritable Bowel Syndrome: 13 people, 22.81%
Neuralgia (pain in one or more nerves): 13 people, 22.81%
Inflammation: 12 people, 21.05%

* Approximation only. Some reports may have incomplete information.

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