Stivarga and Diazepam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Stivarga (regorafenib) and Diazepam (diazepam). Common drug interactions include fatigue among females and gait disturbance among males.

The phase IV clinical study analyzes what interactions people have when they take Stivarga and Diazepam. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Stivarga?

Stivarga has active ingredients of regorafenib. eHealthMe is studying from 9,539 Stivarga users. Check the latest studies of Stivarga.

What is Diazepam?

Diazepam has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 108,384 Diazepam users. Check the latest studies of Diazepam.



On Jul, 20, 2026

15 people who take Stivarga and Diazepam together, and have interactions are studied.

Stivarga and Diazepam drug interactions.

What are the common drug interactions of Stivarga and Diazepam, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Stomatitis (inflammation of mucous membrane of mouth)
  3. Abdominal discomfort
  4. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  5. Death
  6. Diarrhoea
  7. Hyperkalaemia (damage to or disease of the kidney)
  8. Hypertension (high blood pressure)
  9. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
  10. Neuropathy peripheral (surface nerve damage)

male:

  1. Gait disturbance
  2. Pain
  3. Cough
  4. Dehydration (dryness resulting from the removal of water)
  5. Dyspnoea (difficult or laboured respiration)
  6. Haematochezia (passage of stools containing blood)
  7. Hyperkeratosis (thickening of the outer layer of the skin)
  8. Hypoaesthesia (reduced sense of touch or sensation)
  9. Infection
  10. Influenza

What are the common drug interactions of Stivarga and Diazepam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal discomfort
  2. Death
  3. Fatigue (feeling of tiredness)
  4. Hyperkalaemia (damage to or disease of the kidney)
  5. Hypertension (high blood pressure)
  6. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
  7. Neuropathy peripheral (surface nerve damage)
  8. Stomatitis (inflammation of mucous membrane of mouth)
  9. Disease progression
  10. Carcinoembryonic antigen increased

50-59:

n/a

60+:

  1. Gait disturbance
  2. Pain
  3. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  4. Diarrhoea
  5. Fatigue (feeling of tiredness)
  6. Pain in extremity
  7. Rash
  8. White blood cell count decreased
  9. Urinary tract infection
  10. Adverse drug reaction

What are the existing conditions these people have? *

  1. Rectal Cancer (cancer of rectum): 6 people, 40.00%
  2. Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 4 people, 26.67%
  3. Rectosigmoid Cancer (cancer that originates in the rectum and sigmoid colon): 2 people, 13.33%
  4. Hepatocellular Carcinoma (liver cancer): 2 people, 13.33%
  5. Pain In Extremity: 1 person, 6.67%
  6. Pain: 1 person, 6.67%
  7. Osteoporosis (bones weak and more likely to break): 1 person, 6.67%
  8. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 6.67%
  9. Gastrointestinal Stromal Tumor: 1 person, 6.67%
  10. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Stivarga and Diazepam?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Stivarga and Diazepam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Stivarga:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Diazepam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Stivarga and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Diazepam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on regorafenib and diazepam (the active ingredients of Stivarga and Diazepam, respectively), and Stivarga and Diazepam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: