Stivarga and Lasix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Stivarga (regorafenib) and Lasix (furosemide). Common drug interactions include hypothyroidism among females and palmar-plantar erythrodysaesthesia syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Stivarga and Lasix. It is created by eHealthMe based on reports of 84 people who take the same drugs from the FDA, and is updated regularly.

What is Stivarga?

Stivarga has active ingredients of regorafenib. eHealthMe is studying from 9,539 Stivarga users. Check the latest studies of Stivarga.

What is Lasix?

Lasix has active ingredients of furosemide. It is often used in swelling. eHealthMe is studying from 210,439 Lasix users. Check the latest studies of Lasix.

On Jul, 05, 2026

84 people who take Stivarga and Lasix together, and have interactions are studied.

What are the common drug interactions of Stivarga and Lasix, by gender? *:

female:

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Melaena (the passage of black, tarry stools)
White blood cell count decreased
Colon cancer
Rash
Dehydration (dryness resulting from the removal of water)
Nausea (feeling of having an urge to vomit)
Hand-foot-and-mouth disease
Dysphonia (speech disorder attributable to a disorder of phonation)
Fatigue (feeling of tiredness)

male:

Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Decreased appetite
Rash
Septic shock (shock due to blood infection)
Dyspnoea (difficult or laboured respiration)
Colon cancer
Dysphonia (speech disorder attributable to a disorder of phonation)
Constipation
Melaena (the passage of black, tarry stools)
Pain

What are the common drug interactions of Stivarga and Lasix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Diarrhoea
Malaise (a feeling of general discomfort or uneasiness)
Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Anaemia (lack of blood)
Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Melaena (the passage of black, tarry stools)
White blood cell count decreased
Hand-foot-and-mouth disease
Decreased appetite

50-59:

Duodenal ulcer haemorrhage (bleeding duodenal ulcer)
Dysphonia (speech disorder attributable to a disorder of phonation)
Malignant neoplasm of renal pelvis (cancer tumour of ureter)
Oesophageal varices haemorrhage (bleeding from extremely dilated sub-mucosal veins in the lower third of the oesophagus)
Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Pneumonia
Rash
Septic shock (shock due to blood infection)
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Decreased appetite

60+:

Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Decreased appetite
Oedema peripheral (superficial swelling)
Vomiting
Rash
Dehydration (dryness resulting from the removal of water)
Dizziness
Dysphonia (speech disorder attributable to a disorder of phonation)
Hospitalisation
Asthenia (weakness)

What are the existing conditions these people have? *

Colon Cancer: 34 people, 40.48%
Hepatocellular Carcinoma (liver cancer): 16 people, 19.05%
Gastrointestinal Stromal Tumor: 8 people, 9.52%
Diarrhea: 6 people, 7.14%
Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 5 people, 5.95%

* Approximation only. Some reports may have incomplete information.

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