Suboxone and Sucralfate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Suboxone (buprenorphine hydrochloride; naloxone hydrochloride) and Sucralfate (sucralfate). Common drug interactions include chronic kidney disease among females and hepatitis c among males.

The phase IV clinical study analyzes what interactions people have when they take Suboxone and Sucralfate. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Suboxone?

Suboxone has active ingredients of buprenorphine hydrochloride; naloxone hydrochloride. It is often used in opiate withdrawal. eHealthMe is studying from 31,249 Suboxone users. Check the latest studies of Suboxone.

What is Sucralfate?

Sucralfate has active ingredients of sucralfate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 17,548 Sucralfate users. Check the latest studies of Sucralfate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

18 people who take Suboxone and Sucralfate together, and have interactions are studied.

Suboxone and Sucralfate drug interactions.

What are the common drug interactions of Suboxone and Sucralfate, by gender? *:

female:

Chronic kidney disease
Drug ineffective
Malaise (a feeling of general discomfort or uneasiness)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Dizziness
Oral administration complication
Tremor (trembling or shaking movements in one or more parts of your body)
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Acute left ventricular failure (heart attack)
Acute respiratory failure

male:

Hepatitis c
Chronic kidney disease
Drug dependence
Drug ineffective
Overdose
Renal failure (kidney dysfunction)
Spinal fusion surgery

What are the common drug interactions of Suboxone and Sucralfate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anxiety
Pain
Rash
Vomiting
Chronic kidney disease
Hyperhidrosis (abnormally increased sweating)
Nervousness
Pneumonia
Spinal fusion surgery
Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)

50-59:

Drug ineffective
Malaise (a feeling of general discomfort or uneasiness)
Chronic kidney disease
Renal failure (kidney dysfunction)

60+:

Nausea (feeling of having an urge to vomit)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Muscular weakness (muscle weakness)
Onychomycosis (fungal infection of the nail)
Pain in extremity
Renal impairment (severely reduced kidney function)
Skin ulcer
Weight decreased
Dizziness
Oral administration complication

What are the existing conditions these people have? *

Pain: 7 people, 38.89%
Drug Dependence: 5 people, 27.78%
Depression: 5 people, 27.78%
Constipation: 4 people, 22.22%
Migraine (headache): 4 people, 22.22%
Stress And Anxiety: 4 people, 22.22%
Urticaria (rash of round, red welts on the skin that itch intensely): 3 people, 16.67%
Insomnia (sleeplessness): 3 people, 16.67%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 16.67%
Hypersensitivity: 3 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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