Sudafed and Allegra d 24 hour drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sudafed (pseudoephedrine hydrochloride) and Allegra d 24 hour (fexofenadine hydrochloride; pseudoephedrine hydrochloride). Common drug interactions include cholecystitis chronic among females.

The phase IV clinical study analyzes what interactions people have when they take Sudafed and Allegra d 24 hour. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Sudafed?

Sudafed has active ingredients of pseudoephedrine hydrochloride. It is often used in nasal congestion. eHealthMe is studying from 12,944 Sudafed users. Check the latest studies of Sudafed.

What is Allegra d 24 hour?

Allegra d 24 hour has active ingredients of fexofenadine hydrochloride; pseudoephedrine hydrochloride. It is often used in allergies. eHealthMe is studying from 1,427 Allegra d 24 hour users. Check the latest studies of Allegra d 24 hour.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

11 people who take Sudafed and Allegra d 24 hour together, and have interactions are studied.

Sudafed and Allegra d 24 hour drug interactions.

What are the common drug interactions of Sudafed and Allegra D 24 Hour, by gender? *:

female:

  1. Cholecystitis chronic (long lasting infection of gallbladder)
  2. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  3. Back pain
  4. Blood urea increased
  5. Bone disorder
  6. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  7. Cervicitis (inflammation of the uterine cervix)
  8. Chest pain
  9. Colonic polyp (extra part of colon tissue grow in intestine)
  10. Decreased appetite

male:

n/a

What are the common drug interactions of Sudafed and Allegra D 24 Hour, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Cholecystitis chronic (long lasting infection of gallbladder)
  2. Gallbladder disorder
  3. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  4. Cholecystitis acute (rapid infection of gallbladder)
  5. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

50-59:

  1. Abdominal pain
  2. Anaemia (lack of blood)
  3. Cervicitis (inflammation of the uterine cervix)
  4. Chest pain
  5. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  6. Colonic polyp (extra part of colon tissue grow in intestine)
  7. Decreased appetite
  8. Depression
  9. Diarrhoea
  10. Disease progression

60+:

n/a

What are the existing conditions these people have? *

  1. Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 4 people, 36.36%
  2. Osteomyelitis (infection of bone): 4 people, 36.36%
  3. Menopause (end of monthly cycles in women): 4 people, 36.36%
  4. Anaemia (lack of blood): 4 people, 36.36%
  5. Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 3 people, 27.27%
  6. Bipolar Disorder (mood disorder): 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Sudafed and Allegra d 24 hour:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sudafed:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Allegra d 24 hour:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sudafed and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Allegra d 24 hour and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on pseudoephedrine hydrochloride and fexofenadine hydrochloride; pseudoephedrine hydrochloride (the active ingredients of Sudafed and Allegra d 24 hour, respectively), and Sudafed and Allegra d 24 hour (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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