Sular and Pantoprazole drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Sular (nisoldipine) and Pantoprazole (pantoprazole sodium). Common drug interactions include aortic valve sclerosis among females and renal failure among males.
The phase IV clinical study analyzes what interactions people have when they take Sular and Pantoprazole. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.
What is Sular?
Sular has active ingredients of nisoldipine. It is often used in high blood pressure. eHealthMe is studying from 1,757 Sular users. Check the latest studies of Sular.
What is Pantoprazole?
Pantoprazole has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 285,167 Pantoprazole users. Check the latest studies of Pantoprazole.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
44 people who take Sular and Pantoprazole together, and have interactions are studied.

What are the common drug interactions of Sular and Pantoprazole, by gender? *:
female:
- Aortic valve sclerosis (narrowing of the aortic valve)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
- Bipolar disorder (mood disorder)
- Blood pressure diastolic decreased
- Blood triglycerides increased
- Bone density decreased
- Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
- Breath sounds
- Calciphylaxis (is a syndrome with vascular calcium accumulation)
male:
- Renal failure (kidney dysfunction)
- Chronic kidney disease
- Quality of life decreased
- Renal disorder (kidney disease)
- Bone density decreased
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Renal neoplasm (kidney tumour)
- Renal tubular necrosis (death of kidney tubules)
- Upper limb fracture
- Acute pulmonary oedema (sudden deposit of fluid in the lung))
What are the common drug interactions of Sular and Pantoprazole, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Anaemia (lack of blood)
- Anxiety
- Asthenia (weakness)
- Cardiac failure congestive
- Device dislocation
- Dystonia (abnormal muscle tone)
- Emotional disorder
- Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
- Malaise (a feeling of general discomfort or uneasiness)
- Nausea (feeling of having an urge to vomit)
30-39:
- Anxiety
- Depression
- Renal failure (kidney dysfunction)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Chronic kidney disease
- Decreased activity
- Emotional distress
- Fatigue (feeling of tiredness)
- Pain
- Quality of life decreased
40-49:
- Chronic kidney disease
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
50-59:
- Gastric cancer (stomach cancer)
- Glaucoma (increased fluid pressure in the eye with vision loss)
- Intervertebral disc disorder (spinal disc disorder)
- Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
- Kidney infection
- Linitis plastica
- Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
- Neoplasm malignant (cancer tumour)
- Osteoporosis (bones weak and more likely to break)
- Pain
60+:
- Anxiety
- Anaemia (lack of blood)
- Cardiac murmur (an heart sound in valve abnormality)
- Cardioactive drug level increased
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Diarrhoea
- Hypophagia (reduced food intake)
- Impaired healing
- Unresponsive to stimuli
- Abdominal distension
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 27.27%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 22.73%
- High Blood Cholesterol: 7 people, 15.91%
- Pain: 6 people, 13.64%
- Hiv Infection: 4 people, 9.09%
- Diabetes: 4 people, 9.09%
- Blood Pressure Abnormal: 4 people, 9.09%
- Infection: 3 people, 6.82%
* Approximation only. Some reports may have incomplete information.
Do you take Sular and Pantoprazole?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Sular (1,757 reports)
- Pantoprazole (285,167 reports)
Browse all drug interactions of Sular and Pantoprazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Sular:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Pantoprazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sular and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pantoprazole and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on nisoldipine and pantoprazole sodium (the active ingredients of Sular and Pantoprazole, respectively), and Sular and Pantoprazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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