Sulfasalazine and Exforge drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sulfasalazine (sulfasalazine) and Exforge (amlodipine besylate; valsartan). Common drug interactions include pallor among females and ankylosing spondylitis among males.

The phase IV clinical study analyzes what interactions people have when they take Sulfasalazine and Exforge. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Sulfasalazine?

Sulfasalazine has active ingredients of sulfasalazine. It is often used in rheumatoid arthritis. eHealthMe is studying from 96,787 Sulfasalazine users. Check the latest studies of Sulfasalazine.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 13,350 Exforge users. Check the latest studies of Exforge.

On Jul, 27, 2026

30 people who take Sulfasalazine and Exforge together, and have interactions are studied.

Sulfasalazine and Exforge drug interactions.

What are the common drug interactions of Sulfasalazine and Exforge, by gender? *:

female:

Pallor
Pulmonary mass
Red blood cell sedimentation rate increased
Respiratory disorder (respiratory disease)
Rheumatoid factor increased
Skin plaque (red, scaly patches to appear on the skin)
Therapeutic response decreased (less preventive response)
Tooth extraction
Vomiting
Diarrhoea

male:

Ankylosing spondylitis (type of arthritis affecting the spine)
Diarrhoea
Arthralgia (joint pain)
Bacterial infection
Burning sensation
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Colitis ulcerative (inflammation of colon with ulcer)
Comminuted fracture (bone has broken into several pieces)
Constipation
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)

What are the common drug interactions of Sulfasalazine and Exforge, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Arthralgia (joint pain)
Comminuted fracture (bone has broken into several pieces)
Hydronephrosis (water inside the kidney)
Joint swelling
Nephrolithiasis (calculi in the kidneys)
Pyrexia (fever)
Wound infection

40-49:

Sudden hearing loss
Arthralgia (joint pain)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Diarrhoea
Eating disorder
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Migraine (headache)
Nephrolithiasis (calculi in the kidneys)
Pallor
Respiratory disorder (respiratory disease)

50-59:

Pyrexia (fever)
Rectal ulcer (ulcer of rectum)
Sensation of foreign body
Stomatitis (inflammation of mucous membrane of mouth)
Type iv hypersensitivity reaction (delayed type hypersensitivity as the reaction takes two to three days to develop)
Upper respiratory fungal infection
Arthropathy
Bacterial infection
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Nephrolithiasis (calculi in the kidneys)

60+:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Gamma-glutamyltransferase increased
Glomerular filtration rate decreased
Glycosylated haemoglobin increased
Hepatic failure (liver failure)
Intervertebral disc protrusion (spinal disc protrusion)
Leukopenia (less number of white blood cells in blood)
Malignant neoplasm progression (cancer tumour came back)
Menopausal symptoms

What are the existing conditions these people have? *

High Blood Pressure: 16 people, 53.33%
High Blood Cholesterol: 6 people, 20.00%
Ankylosing Spondylitis (type of arthritis affecting the spine): 5 people, 16.67%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 10.00%
Pain: 3 people, 10.00%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 10.00%
Diabetes: 3 people, 10.00%
Diarrhea: 2 people, 6.67%
Arrhythmias (irregular heartbeat): 2 people, 6.67%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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