Sumatriptan succinate and Sodium bicarbonate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sumatriptan succinate (sumatriptan succinate) and Sodium bicarbonate (sodium bicarbonate). Common drug interactions include abortion spontaneous among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Sumatriptan succinate and Sodium bicarbonate. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Sumatriptan succinate?

Sumatriptan succinate has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 9,731 Sumatriptan succinate users. Check the latest studies of Sumatriptan succinate.

What is Sodium bicarbonate?

Sodium bicarbonate has active ingredients of sodium bicarbonate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 27,283 Sodium bicarbonate users. Check the latest studies of Sodium bicarbonate.

On Jul, 15, 2026

47 people who take Sumatriptan succinate and Sodium bicarbonate together, and have interactions are studied.

Sumatriptan succinate and Sodium bicarbonate drug interactions.

What are the common drug interactions of Sumatriptan Succinate and Sodium Bicarbonate, by gender? *:

female:

Abortion spontaneous (naturally occurring miscarriage)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Drug ineffective
Clonus (series of involuntary, rhythmic, muscular contractions and relaxations)
Emotional distress
Hyperhidrosis (abnormally increased sweating)
Hyperreflexia (overactive or over responsive reflexes)
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
Muscle contractions involuntary (uncontrolled muscle contraction)
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)

male:

Chronic kidney disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Renal impairment (severely reduced kidney function)
Anxiety
Emotional distress
Full blood count decreased
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Pain
Rash generalised (rash on most of body parts)

What are the common drug interactions of Sumatriptan Succinate and Sodium Bicarbonate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)

30-39:

Abortion spontaneous (naturally occurring miscarriage)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Clonus (series of involuntary, rhythmic, muscular contractions and relaxations)
Emotional distress
Hyperhidrosis (abnormally increased sweating)
Hyperreflexia (overactive or over responsive reflexes)
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
Muscle contractions involuntary (uncontrolled muscle contraction)
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
Myalgia (muscle pain)

40-49:

Blood calcium decreased
Dehydration (dryness resulting from the removal of water)
Haemoglobin decreased
Nausea (feeling of having an urge to vomit)
Vomiting

50-59:

Liver transplant rejection (failure of liver transplant)
Pain
Abdominal pain
Acute sinusitis
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Bone atrophy (decrease in bone mass)
Breast mass
Bronchial hyperreactivity

60+:

Eye pain
Full blood count decreased
Herpes simplex (herpes simplex is a common viral infection)
Rash generalised (rash on most of body parts)

What are the existing conditions these people have? *

Morning Sickness (sickness in morning during pregnancy): 16 people, 34.04%
Nausea (feeling of having an urge to vomit): 16 people, 34.04%
Nausea And Vomiting: 15 people, 31.91%
Hyperemesis Gravidarum (a condition characterized by severe nausea, vomiting, weight loss, and electrolyte disturbance): 14 people, 29.79%
Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 13 people, 27.66%
Fever: 12 people, 25.53%
Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 12 people, 25.53%
Body Temperature Increased: 11 people, 23.40%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 8.51%
Multiple Myeloma (cancer of the plasma cells): 4 people, 8.51%

* Approximation only. Some reports may have incomplete information.

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