Sumatriptan and Vioxx drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sumatriptan (sumatriptan succinate) and Vioxx (rofecoxib). Common drug interactions include depression among females.

The phase IV clinical study analyzes what interactions people have when they take Sumatriptan and Vioxx. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Sumatriptan?

Sumatriptan has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 18,159 Sumatriptan users. Check the latest studies of Sumatriptan.

What is Vioxx?

Vioxx has active ingredients of rofecoxib. It is often used in arthritis. eHealthMe is studying from 110,130 Vioxx users. Check the latest studies of Vioxx.

On Jul, 10, 2026

54 people who take Sumatriptan and Vioxx together, and have interactions are studied.

Sumatriptan and Vioxx drug interactions.

What are the common drug interactions of Sumatriptan and Vioxx, by gender? *:

female:

Depression
Anxiety
Oesophageal pain
Pneumonia
Pruritus (severe itching of the skin)
Agitation (state of anxiety or nervous excitement)
Cystitis (inflammation of the wall of the bladder)
Diarrhoea
Fluid retention (an abnormal accumulation of fluid in the blood)
Hallucination (an experience involving the perception of something not present)

male:

n/a

What are the common drug interactions of Sumatriptan and Vioxx, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Erythrocyte sedimentation rate increased
Hypoaesthesia (reduced sense of touch or sensation)
Joint stiffness
Joint swelling
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Polyarthralgia (joint pain)
Pruritus (severe itching of the skin)
Rash generalised (rash on most of body parts)

50-59:

Abdominal pain
Rash
Dizziness
Agitation (state of anxiety or nervous excitement)
Cystitis (inflammation of the wall of the bladder)
Diarrhoea
Fibromyalgia (a long-term condition which causes pain all over the body)
Fluid retention (an abnormal accumulation of fluid in the blood)
Hallucination (an experience involving the perception of something not present)
Hyperhidrosis (abnormally increased sweating)

60+:

Abdominal mass (localized enlargement or swelling in the human abdomen)
Affect lability (emotional incontinence)
Burning sensation
Butterfly rash
Cataract (clouding of the lens inside the eye)
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Chorea (abnormal involuntary movement disorder)
Colonic polyp (extra part of colon tissue grow in intestine)
Confusional state
Contusion (a type of hematoma of tissue in which capillaries)

What are the existing conditions these people have? *

High Blood Cholesterol: 45 people, 83.33%
Abdominal Pain: 43 people, 79.63%
Fluid Retention (an abnormal accumulation of fluid in the blood): 43 people, 79.63%
Itching: 43 people, 79.63%
Type 2 Diabetes: 43 people, 79.63%
Stress And Anxiety: 43 people, 79.63%
Stomatitis (inflammation of mucous membrane of mouth): 43 people, 79.63%
Rashes (redness): 43 people, 79.63%
Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 43 people, 79.63%
Malaise (a feeling of general discomfort or uneasiness): 43 people, 79.63%

* Approximation only. Some reports may have incomplete information.

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