Suprax and Methotrexate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Suprax (cefixime) and Methotrexate (methotrexate sodium). Common drug interactions include plasma cell myeloma among females and haematotoxicity among males.

The phase IV clinical study analyzes what interactions people have when they take Suprax and Methotrexate. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Suprax?

Suprax has active ingredients of cefixime. eHealthMe is studying from 965 Suprax users. Check the latest studies of Suprax.

What is Methotrexate?

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. eHealthMe is studying from 604,312 Methotrexate users. Check the latest studies of Methotrexate.

On Jul, 08, 2026

12 people who take Suprax and Methotrexate together, and have interactions are studied.

Suprax and Methotrexate drug interactions.

What are the common drug interactions of Suprax and Methotrexate, by gender? *:

female:

Plasma cell myeloma (cancer that begins in plasma cells)
Chest discomfort
Dizziness
Drug hypersensitivity
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Dysstasia (difficulty in standing)
Headache (pain in head)
Lethargy (tiredness)
Listless (lack of interest, energy, or spirit)

male:

Haematotoxicity (toxins that destroy red blood cells)
Nausea (feeling of having an urge to vomit)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Vomiting
Hyperkalaemia (damage to or disease of the kidney)
Peripheral motor neuropathy (muscles in the body become progressively weaker over months to years)
Peripheral sensory neuropathy (damage to one or more of your peripheral nerves)
Sinus arrhythmia (a naturally occurring variation in heart rate that occurs during a breathing cycle)

What are the common drug interactions of Suprax and Methotrexate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Haematotoxicity (toxins that destroy red blood cells)
Nausea (feeling of having an urge to vomit)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Vomiting
Hyperkalaemia (damage to or disease of the kidney)
Sinus arrhythmia (a naturally occurring variation in heart rate that occurs during a breathing cycle)

10-19:

Peripheral motor neuropathy (muscles in the body become progressively weaker over months to years)
Peripheral sensory neuropathy (damage to one or more of your peripheral nerves)

20-29:

n/a

30-39:

n/a

40-49:

Tuberculous pleurisy (an inflammation of lung covering plura by mycobacterium tuberculosis)

50-59:

Listless (lack of interest, energy, or spirit)
Palpitations (feelings or sensations that your heart is pounding or racing)
Chest discomfort
Dizziness
Dyspnoea (difficult or laboured respiration)
Dysstasia (difficulty in standing)
Headache (pain in head)
Lethargy (tiredness)

60+:

Arthralgia (joint pain)
Gait disturbance
Plasma cell myeloma (cancer that begins in plasma cells)
Drug hypersensitivity

What are the existing conditions these people have? *

Urinary Tract Infection: 4 people, 33.33%
Tumor: 3 people, 25.00%
Dermatitis Allergic (inflammation of the skin due allergic reaction): 3 people, 25.00%
Sinusitis (inflammation of sinus): 2 people, 16.67%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 2 people, 16.67%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 8.33%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 8.33%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 8.33%
Immunodeficiency Disorders: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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