Sutent and Hydramine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sutent (sunitinib malate) and Hydramine (diphenhydramine hydrochloride). Common drug interactions include asthenia among females and decreased appetite among males.

The phase IV clinical study analyzes what interactions people have when they take Sutent and Hydramine. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Sutent?

Sutent has active ingredients of sunitinib malate. It is often used in renal cell carcinoma. eHealthMe is studying from 44,554 Sutent users. Check the latest studies of Sutent.

What is Hydramine?

Hydramine has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 114,900 Hydramine users. Check the latest studies of Hydramine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

59 people who take Sutent and Hydramine together, and have interactions are studied.

What are the common drug interactions of Sutent and Hydramine, by gender? *:

female:

Asthenia (weakness)
Dyspepsia (indigestion)
Nausea (feeling of having an urge to vomit)
Rash
Thrombocytopenia (decrease of platelets in blood)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Feeding disorder (when children refuse to eat certain food groups)
Gingival bleeding (bleeding gums)
Hyperaesthesia
Hypogeusia (reduced ability to taste things (to taste sweet, sour, bitter, or salty substances))

male:

Decreased appetite
Nausea (feeling of having an urge to vomit)
Skin exfoliation (removal of the oldest dead skin cells)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Weight decreased
Pain in extremity
Impaired healing
Alopecia (absence of hair from areas of the body)
Diarrhoea
Faeces discoloured

What are the common drug interactions of Sutent and Hydramine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)

30-39:

Dry mouth
Oral pain

40-49:

n/a

50-59:

Nausea (feeling of having an urge to vomit)
Rash
Thrombocytopenia (decrease of platelets in blood)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Feeding disorder (when children refuse to eat certain food groups)
Gingival bleeding (bleeding gums)
Hyperaesthesia
Hypogeusia (reduced ability to taste things (to taste sweet, sour, bitter, or salty substances))
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Leukopenia (less number of white blood cells in blood)

60+:

Decreased appetite
Nausea (feeling of having an urge to vomit)
Pain in extremity
Diarrhoea
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Neoplasm progression (growth of tumour)
Dehydration (dryness resulting from the removal of water)
Alopecia (absence of hair from areas of the body)
Impaired healing
Skin irritation

What are the existing conditions these people have? *

Gastrointestinal Stromal Tumor: 13 people, 22.03%
Nausea (feeling of having an urge to vomit): 9 people, 15.25%
Wheezing (a high-pitched whistling sound made while you breath): 8 people, 13.56%
High Blood Pressure: 6 people, 10.17%
Stress And Anxiety: 4 people, 6.78%
Neoplasm Malignant (cancer tumour): 4 people, 6.78%
Diabetes: 4 people, 6.78%
Sleep Disorder: 3 people, 5.08%
Renal Cell Carcinoma Stage Unspecified (kidney cancer in unknown stage): 3 people, 5.08%
Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 3 people, 5.08%

* Approximation only. Some reports may have incomplete information.

Do you take Sutent and Hydramine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously