Symbicort and Hydrodiuril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Symbicort (budesonide; formoterol fumarate dihydrate) and Hydrodiuril (hydrochlorothiazide). Common drug interactions include anxiety among females and cough among males.

The phase IV clinical study analyzes what interactions people have when they take Symbicort and Hydrodiuril. It is created by eHealthMe based on reports of 72 people who take the same drugs from the FDA, and is updated regularly.

What is Symbicort?

Symbicort has active ingredients of budesonide; formoterol fumarate dihydrate. It is often used in asthma. eHealthMe is studying from 114,792 Symbicort users. Check the latest studies of Symbicort.

What is Hydrodiuril?

Hydrodiuril has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 4,211 Hydrodiuril users. Check the latest studies of Hydrodiuril.



On Aug, 09, 2026

72 people who take Symbicort and Hydrodiuril together, and have interactions are studied.

Symbicort and Hydrodiuril drug interactions.

What are the common drug interactions of Symbicort and Hydrodiuril, by gender? *:

female:

  1. Anxiety
  2. Urinary tract infection
  3. Abdominal pain
  4. Back pain
  5. Eating disorder
  6. Head discomfort
  7. Hot flush (sudden feelings of heat)
  8. Muscle tightness
  9. Photophobia (extreme sensitivity to light)
  10. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)

male:

  1. Cough
  2. Dyspnoea (difficult or laboured respiration)
  3. Osteoporosis (bones weak and more likely to break)
  4. Renal tubular necrosis (death of kidney tubules)
  5. Respiratory failure (inadequate gas exchange by the respiratory system)
  6. Sepsis (a severe blood infection that can lead to organ failure and death)
  7. Bronchitis bacterial (inflammation of the mucous membrane in the bronchial tubes due to bacterial infection)
  8. Ear infection
  9. Haemorrhagic anaemia (anaemia due to excessive bleeding)
  10. Acute respiratory failure

What are the common drug interactions of Symbicort and Hydrodiuril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Drug hypersensitivity
  2. Urticaria (rash of round, red welts on the skin that itch intensely)

40-49:

  1. Nausea (feeling of having an urge to vomit)
  2. Dyspnoea (difficult or laboured respiration)
  3. Headache (pain in head)
  4. Oral mucosal blistering (mouth ulcer)
  5. Pyrexia (fever)
  6. Anxiety
  7. Arthralgia (joint pain)
  8. Back pain
  9. Bipolar disorder (mood disorder)
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

50-59:

  1. Angioedema (rapid swelling of the dermis)
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Ankle fracture
  4. Arthralgia (joint pain)
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  6. Bone disorder
  7. Constipation
  8. Cough
  9. Crying
  10. Depression

60+:

  1. Fatigue (feeling of tiredness)
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Carotid artery stenosis (narrowing of carotid artery)
  4. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
  5. Hepatitis (inflammation of the liver)
  6. Mitral valve disease mixed (disease process involving one or more of the valves of the heart)
  7. Cardiac failure congestive
  8. Fall
  9. Left ventricular failure (left ventricle fails to contract forcefully)
  10. Lower limb fracture

What are the existing conditions these people have? *

  1. Pain: 12 people, 16.67%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 15.28%
  3. High Blood Cholesterol: 11 people, 15.28%
  4. Wheezing (a high-pitched whistling sound made while you breath): 10 people, 13.89%
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 9 people, 12.50%
  6. Depression: 9 people, 12.50%
  7. Dyspnea (difficult or laboured breathing): 9 people, 12.50%
  8. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 9 people, 12.50%
  9. Nausea (feeling of having an urge to vomit): 7 people, 9.72%
  10. Muscle Spasms (muscle contraction): 6 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Symbicort and Hydrodiuril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Symbicort:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hydrodiuril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Symbicort and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydrodiuril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on budesonide; formoterol fumarate dihydrate and hydrochlorothiazide (the active ingredients of Symbicort and Hydrodiuril, respectively), and Symbicort and Hydrodiuril (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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