Symproic and Xtandi drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Symproic (naldemedine tosylate) and Xtandi (enzalutamide). Common drug interactions include nausea among males.
The phase IV clinical study analyzes what interactions people have when they take Symproic and Xtandi. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Symproic?
Symproic has active ingredients of naldemedine tosylate. eHealthMe is studying from 1,487 Symproic users. Check the latest studies of Symproic.
What is Xtandi?
Xtandi has active ingredients of enzalutamide. eHealthMe is studying from 51,498 Xtandi users. Check the latest studies of Xtandi.
13 people who take Symproic and Xtandi together, and have interactions are studied.

What are the common drug interactions of Symproic and Xtandi, by gender? *:
female:
n/a
male:
- Nausea (feeling of having an urge to vomit)
- Anaemia (lack of blood)
- Dehydration (dryness resulting from the removal of water)
- Depressed level of consciousness
- Dyspnoea (difficult or laboured respiration)
- Epistaxis (bleed from the nose)
- Erythema (redness of the skin)
- Haemoglobin decreased
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
- Metastases to liver (cancer spreads to liver)
What are the common drug interactions of Symproic and Xtandi, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Nausea (feeling of having an urge to vomit)
- Anaemia (lack of blood)
- Cardiac failure congestive
- Chest pain
- Cystitis (inflammation of the wall of the bladder)
- Decreased appetite
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Dehydration (dryness resulting from the removal of water)
- Depressed level of consciousness
- Dizziness
What are the existing conditions these people have? *
- Prostate Cancer: 3 people, 23.08%
- Enlarged Prostate: 3 people, 23.08%
- Stable Angina (a constant chest pain): 3 people, 23.08%
- Stomatitis (inflammation of mucous membrane of mouth): 2 people, 15.38%
- Lumbar Spinal Stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone): 2 people, 15.38%
- Constipation: 2 people, 15.38%
- Insomnia (sleeplessness): 2 people, 15.38%
- High Blood Pressure: 2 people, 15.38%
- Nausea (feeling of having an urge to vomit): 2 people, 15.38%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 15.38%
* Approximation only. Some reports may have incomplete information.
Do you take Symproic and Xtandi?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Symproic and Xtandi:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Symproic:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Xtandi:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Symproic and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Xtandi and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on naldemedine tosylate and enzalutamide (the active ingredients of Symproic and Xtandi, respectively), and Symproic and Xtandi (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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