Synalar and Kenalog drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Synalar (fluocinolone acetonide) and Kenalog (triamcinolone acetonide). Common drug interactions include cardiac disorder among females and acute myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Synalar and Kenalog. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Synalar?

Synalar has active ingredients of fluocinolone acetonide. eHealthMe is studying from 332 Synalar users. Check the latest studies of Synalar.

What is Kenalog?

Kenalog has active ingredients of triamcinolone acetonide. It is often used in pain. eHealthMe is studying from 10,692 Kenalog users. Check the latest studies of Kenalog.



On Jul, 17, 2026

21 people who take Synalar and Kenalog together, and have interactions are studied.

Synalar and Kenalog drug interactions.

What are the common drug interactions of Synalar and Kenalog, by gender? *:

female:

  1. Cardiac disorder
  2. Hypertension (high blood pressure)
  3. Migraine (headache)
  4. Type 1 diabetes mellitus
  5. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  6. Cardiac failure congestive
  7. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  8. Contusion (a type of hematoma of tissue in which capillaries)
  9. Cough
  10. Cushing's syndrome (obesity, a rounded face, increased fat)

male:

  1. Acute myocardial infarction (acute heart attack)
  2. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  3. Pleural effusion (water on the lungs)
  4. Pneumonia
  5. Pulmonary oedema (fluid accumulation in the lungs)
  6. Decreased appetite
  7. Diarrhoea
  8. Lethargy (tiredness)
  9. Nausea (feeling of having an urge to vomit)
  10. Staphylococcal osteomyelitis (inflammation of bone or bone marrow, usually due to staphylococcus bacterial infection)

What are the common drug interactions of Synalar and Kenalog, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Cough
  3. Cushing's syndrome (obesity, a rounded face, increased fat)
  4. Growth retarded (delayed growth)
  5. Hypertension (high blood pressure)
  6. Metabolic disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues)
  7. Scar
  8. Skin striae (irregular areas of skin that look like bands, stripes, or lines)
  9. Vomiting
  10. Wheezing (a high-pitched whistling sound made while you breath)

10-19:

n/a

20-29:

  1. Cardiac disorder
  2. Migraine (headache)
  3. Type 1 diabetes mellitus
  4. Cardiac failure congestive
  5. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  6. Hypoglycaemia (deficiency of glucose in the bloodstream)
  7. Joint injury
  8. Thrombosis (formation of a blood clot inside a blood vessel)
  9. Viral cardiomyopathy (weakness in the muscle of the heart due to viral infection)

30-39:

n/a

40-49:

  1. Drug ineffective

50-59:

  1. Acute myocardial infarction (acute heart attack)
  2. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  3. Asthenia (weakness)
  4. Atelectasis (partial or complete collapse of the lung)
  5. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  6. Emotional distress
  7. Graft complication
  8. Headache (pain in head)
  9. Plantar erythema (soles of the feet)
  10. Pleural effusion (water on the lungs)

60+:

  1. Contusion (a type of hematoma of tissue in which capillaries)
  2. Death
  3. Fall
  4. Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
  5. Large intestine perforation (hole in large intestine)
  6. Optic neuritis (optic nerve inflammation)
  7. Portal hypertension (increase in the blood pressure within a system of veins called the portal venous system)
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Varices oesophageal (enlarged and swollen veins at the bottom of the oesophagus, near the stomach)

What are the existing conditions these people have? *

  1. High Blood Pressure: 5 people, 23.81%
  2. Thrombosis (formation of a blood clot inside a blood vessel): 4 people, 19.05%
  3. Periarthritis (inflammation of the external coats of an artery and of the tissues around the artery): 4 people, 19.05%
  4. Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 4 people, 19.05%
  5. Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 4 people, 19.05%
  6. Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 4 people, 19.05%
  7. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 19.05%
  8. Abdominal Pain: 4 people, 19.05%
  9. Stress And Anxiety: 2 people, 9.52%
  10. Sleep Disorder: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Synalar and Kenalog?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Synalar and Kenalog:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Synalar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Kenalog:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Synalar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Kenalog and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on fluocinolone acetonide and triamcinolone acetonide (the active ingredients of Synalar and Kenalog, respectively), and Synalar and Kenalog (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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