Synalar and Omeprazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Synalar (fluocinolone acetonide) and Omeprazole (omeprazole). Common drug interactions include anal fistula among females and haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Synalar and Omeprazole. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Synalar?

Synalar has active ingredients of fluocinolone acetonide. eHealthMe is studying from 332 Synalar users. Check the latest studies of Synalar.

What is Omeprazole?

Omeprazole has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 410,631 Omeprazole users. Check the latest studies of Omeprazole.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

55 people who take Synalar and Omeprazole together, and have interactions are studied.

Synalar and Omeprazole drug interactions.

What are the common drug interactions of Synalar and Omeprazole, by gender? *:

female:

Anal fistula
Erythema multiforme (a type of hypersensitivity reaction)
Viral skin infection
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Rash
Cellulitis (infection under the skin)
Ear pain
Faecaloma (hard mass of fecal matter)
Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
Breast abscess

male:

Haemorrhage (bleeding)
Headache (pain in head)
Blood alkaline phosphatase increased
Cellulitis (infection under the skin)
Dyspnoea (difficult or laboured respiration)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Neutropenic infection (infection with less neutrophil numbers in blood)
Pemphigoid (tense blisters on the skin)
Pulmonary alveolar haemorrhage (acute bleeding)
Pyrexia (fever)

What are the common drug interactions of Synalar and Omeprazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anal fistula
Erythema multiforme (a type of hypersensitivity reaction)
Viral skin infection
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Rash
Vasculitis (inflammation of a blood vessel or blood vessels)
Faecaloma (hard mass of fecal matter)
Rectal stenosis (narrowing of rectum)
Hypophagia (reduced food intake)

20-29:

n/a

30-39:

n/a

40-49:

Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
Cellulitis (infection under the skin)
Febrile neutropenia (fever with reduced white blood cells)
Thrombocytopenia (decrease of platelets in blood)

50-59:

Headache (pain in head)
Plantar erythema (soles of the feet)
Decreased appetite
Diarrhoea
Lethargy (tiredness)
Nausea (feeling of having an urge to vomit)
Vomiting
Insomnia (sleeplessness)

60+:

Catheter site haemorrhage (bleeding at catheter site)
Haemorrhage (bleeding)
Nausea (feeling of having an urge to vomit)
Confusional state
Delirium (wild excitement)
Foot fracture
Hand fracture
Hypertransaminasaemia
Joint injury
Limb injury

What are the existing conditions these people have? *

Pain: 13 people, 23.64%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 12 people, 21.82%
Vasculitis (inflammation of a blood vessel or blood vessels): 10 people, 18.18%
Rashes (redness): 10 people, 18.18%
Abdominal Pain: 8 people, 14.55%
Skin Infection: 8 people, 14.55%
Fungal Skin Infection: 8 people, 14.55%
Hypophagia (reduced food intake): 8 people, 14.55%
Rickets (softening of bones): 6 people, 10.91%
Procedural Pain: 6 people, 10.91%

* Approximation only. Some reports may have incomplete information.

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