Synthroid and Adderall 30 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Synthroid (levothyroxine sodium) and Adderall 30 (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate). Common drug interactions include abscess among females and azotaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Synthroid and Adderall 30. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Synthroid?

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 249,202 Synthroid users. Check the latest studies of Synthroid.

What is Adderall 30?

Adderall 30 has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 2,045 Adderall 30 users. Check the latest studies of Adderall 30.

On Aug, 03, 2026

14 people who take Synthroid and Adderall 30 together, and have interactions are studied.

Synthroid and Adderall 30 drug interactions.

What are the common drug interactions of Synthroid and Adderall 30, by gender? *:

female:

Abscess (pus)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Bronchopleural fistula
Cardiomegaly (increased size of heart than normal)
Cerebrovascular disorder (disease of brain)
Cervical spinal stenosis (narrowing of the spinal canal in the neck)
Chest pain
Cyst (a closed sac)
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Empyema (collection of pus in a cavity in the body)

male:

Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Blood potassium increased
Gait disturbance
Hypernatraemia (an abnormally high plasma concentration of sodium ions)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Muscular weakness (muscle weakness)
Nephrogenic diabetes insipidus (a disorder in which a defect in the small tubes (tubules) in the kidneys causes a person to pass a large amount of urine)
Pneumonia
Renal failure acute (rapid kidney dysfunction)

What are the common drug interactions of Synthroid and Adderall 30, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Fatigue (feeling of tiredness)
Hypersomnia (excessive daytime sleepiness (eds))

30-39:

Anxiety
Disturbance in attention
Drug effect decreased
Drug level fluctuating
Drug toxicity
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
Partial seizures (seizures which affect only a part of the brain at onset)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Vision blurred

40-49:

Appendicitis perforated (perforated appendicitis is a condition in which an inflamed appendix bursts)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Diarrhoea
Escherichia infection (bacterial infection by escherichia coli)
Haematocrit decreased
Haematocrit increased
Haemoglobin decreased
Haemoglobin increased
Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bronchopleural fistula
Cardiomegaly (increased size of heart than normal)
Cerebrovascular disorder (disease of brain)
Cervical spinal stenosis (narrowing of the spinal canal in the neck)
Chest pain
Cyst (a closed sac)
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Empyema (collection of pus in a cavity in the body)

60+:

Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Blood potassium increased
Gait disturbance
Hypernatraemia (an abnormally high plasma concentration of sodium ions)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Muscular weakness (muscle weakness)
Nephrogenic diabetes insipidus (a disorder in which a defect in the small tubes (tubules) in the kidneys causes a person to pass a large amount of urine)
Pneumonia
Renal failure acute (rapid kidney dysfunction)

What are the existing conditions these people have? *

Depression: 4 people, 28.57%
Bone Density Abnormal: 4 people, 28.57%
Neck Injury: 3 people, 21.43%
Stress And Anxiety: 2 people, 14.29%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 14.29%
Thyroid Diseases: 1 person, 7.14%
Muscle Spasms (muscle contraction): 1 person, 7.14%
Joint Pain: 1 person, 7.14%
Hypersensitivity: 1 person, 7.14%
High Blood Pressure: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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