Synthroid and Azactam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Synthroid (levothyroxine sodium) and Azactam (aztreonam). Common drug interactions include renal failure among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Synthroid and Azactam. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Synthroid?

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 249,194 Synthroid users. Check the latest studies of Synthroid.

What is Azactam?

Azactam has active ingredients of aztreonam. eHealthMe is studying from 1,044 Azactam users. Check the latest studies of Azactam.

On Feb, 11, 2026

12 people who take Synthroid and Azactam together, and have interactions are studied.

Synthroid and Azactam drug interactions.

What are the common drug interactions of Synthroid and Azactam, by gender? *:

female:

Renal failure (kidney dysfunction)
Thrombocytopenia (decrease of platelets in blood)
Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Blood creatine increased
Cardiac failure congestive
Chronic obstructive airways disease
Coagulopathy (blood's ability to clot is impaired)
Hepatic necrosis (large portions of liver die off due to severe liver disease)
Hepatitis chronic active
Hyperbilirubinaemia (excess of bilirubin in the blood)

male:

Anaemia (lack of blood)
Gall bladder perforation (hole in gallbladder)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Heparin-induced thrombocytopenia
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Sepsis (a severe blood infection that can lead to organ failure and death)
Septicaemia staphylococcal (blood infection with bacteria)

What are the common drug interactions of Synthroid and Azactam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Chronic kidney disease
Rash
Renal failure (kidney dysfunction)
Urticaria (rash of round, red welts on the skin that itch intensely)

60+:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Blood creatinine increased
Gall bladder perforation (hole in gallbladder)
Heparin-induced thrombocytopenia
Hepatic necrosis (large portions of liver die off due to severe liver disease)
Hepatitis chronic active
Hyperbilirubinaemia (excess of bilirubin in the blood)
Melaena (the passage of black, tarry stools)
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Nephrogenic anaemia (anaemia due to kidney disease)

What are the existing conditions these people have? *

Staphylococcal Infection (an infection with staphylococcus bacteria): 3 people, 25.00%
High Blood Pressure: 2 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 16.67%
Thyroid Diseases: 1 person, 8.33%
Pain: 1 person, 8.33%
Osteomyelitis Chronic (long lasting infection of bone marrow): 1 person, 8.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 8.33%
Chronic Kidney Disease: 1 person, 8.33%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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