Synthroid and Coversyl plus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Synthroid (levothyroxine sodium) and Coversyl plus (perindopril arginine; indapamide hemihydrate). Common drug interactions include lung neoplasm malignant among females and blindness among males.

The phase IV clinical study analyzes what interactions people have when they take Synthroid and Coversyl plus. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Synthroid?

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 249,198 Synthroid users. Check the latest studies of Synthroid.

What is Coversyl plus?

Coversyl plus has active ingredients of perindopril arginine; indapamide hemihydrate. eHealthMe is studying from 412 Coversyl plus users. Check the latest studies of Coversyl plus.

On Jul, 17, 2026

30 people who take Synthroid and Coversyl plus together, and have interactions are studied.

Synthroid and Coversyl plus drug interactions.

What are the common drug interactions of Synthroid and Coversyl Plus, by gender? *:

female:

Lung neoplasm malignant (cancer tumour of lung)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Rash
Sinusitis (inflammation of sinus)
Abdominal pain
Abdominal pain upper
Anaphylactic reaction (serious allergic reaction)
Arthropathy
Asthma
Bacterial infection

male:

Blindness
Therapeutic response unexpected

What are the common drug interactions of Synthroid and Coversyl Plus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Arthralgia (joint pain)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Anxiety
Clubbing (deformity of the fingers and fingernails)
Endometrial cancer
Ingrowing nail
Lung cancer metastatic (lung cancer spreads to other parts)
Lung neoplasm malignant (cancer tumour of lung)
Pain
Peau d'orange (orange peel skin)

50-59:

Abdominal pain
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Decreased appetite
Diarrhoea
Drug intolerance (drug sensitivity)
Headache (pain in head)
Infection
Metastasis (spreadable cancer to other organ from origin)
Palpitations (feelings or sensations that your heart is pounding or racing)
Pancreatic carcinoma (pancreatic cancer)

60+:

Chest pain
Anxiety
Bacterial infection
Blood pressure fluctuation
Body temperature decreased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Conjunctivitis (pink eye)
Contusion (a type of hematoma of tissue in which capillaries)
Defaecation urgency (a sudden compelling urge to defecate)
Erythema (redness of the skin)

What are the existing conditions these people have? *

Stress And Anxiety: 8 people, 26.67%
Affective Disorder (mental disorder): 8 people, 26.67%
High Blood Pressure: 5 people, 16.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 13.33%
Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain): 4 people, 13.33%
Type 2 Diabetes: 3 people, 10.00%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 10.00%
Diabetes: 3 people, 10.00%
Weight Loss: 2 people, 6.67%
Joint Pain: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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