Synthroid and Pomalidomide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Synthroid (levothyroxine sodium) and Pomalidomide (pomalidomide). Common drug interactions include drug hypersensitivity among females and thrombocytopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Synthroid and Pomalidomide. It is created by eHealthMe based on reports of 62 people who take the same drugs from the FDA, and is updated regularly.

What is Synthroid?

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 249,198 Synthroid users. Check the latest studies of Synthroid.

What is Pomalidomide?

Pomalidomide has active ingredients of pomalidomide. eHealthMe is studying from 14,524 Pomalidomide users. Check the latest studies of Pomalidomide.



On Jul, 20, 2026

62 people who take Synthroid and Pomalidomide together, and have interactions are studied.

Synthroid and Pomalidomide drug interactions.

What are the common drug interactions of Synthroid and Pomalidomide, by gender? *:

female:

  1. Drug hypersensitivity
  2. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  3. Pneumonia
  4. Fatigue (feeling of tiredness)
  5. Hypoaesthesia (reduced sense of touch or sensation)
  6. Insomnia (sleeplessness)
  7. Rash
  8. Urinary tract infection
  9. Back pain
  10. Drug ineffective

male:

  1. Thrombocytopenia (decrease of platelets in blood)
  2. Full blood count decreased
  3. Monoclonal immunoglobulin present
  4. Pulmonary embolism (blockage of the main artery of the lung)
  5. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  6. Arthralgia (joint pain)
  7. Blood electrolytes decreased
  8. Cellulitis (infection under the skin)
  9. Dehydration (dryness resulting from the removal of water)
  10. Dizziness

What are the common drug interactions of Synthroid and Pomalidomide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Urinary tract infection
  2. Anaemia (lack of blood)
  3. Fatigue (feeling of tiredness)
  4. Pulmonary embolism (blockage of the main artery of the lung)
  5. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  6. Thrombocytopenia (decrease of platelets in blood)
  7. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  8. Febrile neutropenia (fever with reduced white blood cells)
  9. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  10. Hypercalcaemia (elevated calcium (ca+) level in the blood)

60+:

  1. Drug hypersensitivity
  2. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  3. Insomnia (sleeplessness)
  4. Peripheral swelling
  5. Pneumonia
  6. Back pain
  7. Fatigue (feeling of tiredness)
  8. Lacrimation increased
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Monoclonal immunoglobulin present

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 54 people, 87.10%
  2. High Blood Pressure: 6 people, 9.68%
  3. Hypokalemia (low potassium): 4 people, 6.45%
  4. Dyspnea (difficult or laboured breathing): 4 people, 6.45%

* Approximation only. Some reports may have incomplete information.

Do you take Synthroid and Pomalidomide?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Synthroid and Pomalidomide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Synthroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pomalidomide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Synthroid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pomalidomide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium and pomalidomide (the active ingredients of Synthroid and Pomalidomide, respectively), and Synthroid and Pomalidomide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: