Synthroid and Prazosin hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Synthroid (levothyroxine sodium) and Prazosin hydrochloride (prazosin hydrochloride). Common drug interactions include loss of consciousness among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Synthroid and Prazosin hydrochloride. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Synthroid?

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 249,198 Synthroid users. Check the latest studies of Synthroid.

What is Prazosin hydrochloride?

Prazosin hydrochloride has active ingredients of prazosin hydrochloride. It is often used in post-traumatic stress disorder. eHealthMe is studying from 1,455 Prazosin hydrochloride users. Check the latest studies of Prazosin hydrochloride.

On Jul, 16, 2026

31 people who take Synthroid and Prazosin hydrochloride together, and have interactions are studied.

Synthroid and Prazosin hydrochloride drug interactions.

What are the common drug interactions of Synthroid and Prazosin Hydrochloride, by gender? *:

female:

Loss of consciousness
Lymphadenitis (inflammation or enlargement of a lymph node)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Weight decreased
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Atrioventricular block first degree (heart block first degree)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
Chills (felling of cold)

male:

Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Dyspnoea (difficult or laboured respiration)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Insomnia (sleeplessness)
Mobility decreased (ability to move is reduced)
Muscular weakness (muscle weakness)
Pain
Skin lesion
Abdominal distension

What are the common drug interactions of Synthroid and Prazosin Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Ear infection
Head injury
Influenza
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
Rash
Respiratory tract infection
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Sinusitis (inflammation of sinus)
Skin infection

40-49:

Adrenal adenoma (benign tumour of the glandular type (adenoma) in the adrenal gland)
Blood alkaline phosphatase increased
Blood chloride decreased
Blood glucose increased
Cardiac disorder
Cardiac failure congestive
Food poisoning (poison in food)
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Headache (pain in head)
Hypoxia (low oxygen in tissues)

50-59:

Abdominal pain
Catheter site inflammation (infection at catheter site)
Dehydration (dryness resulting from the removal of water)
Dyspnoea exertional (breathlessness or shortness of breath)
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Fluid retention (an abnormal accumulation of fluid in the blood)
Kidney infection
Knee arthroplasty
Pyrexia (fever)
Staphylococcal infection (an infection with staphylococcus bacteria)

60+:

Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Injury
Pain
Social problem
Synovitis (inflammation of the synovial membrane)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diarrhoea

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 11 people, 35.48%
Dehydration (dryness resulting from the removal of water): 6 people, 19.35%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 2 people, 6.45%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 6.45%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 6.45%
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract): 2 people, 6.45%
Bipolar Disorder (mood disorder): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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