Synthroid and Viracept drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Synthroid (levothyroxine sodium) and Viracept (nelfinavir mesylate). Common drug interactions include abortion spontaneous among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Synthroid and Viracept. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Synthroid?

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 249,198 Synthroid users. Check the latest studies of Synthroid.

What is Viracept?

Viracept has active ingredients of nelfinavir mesylate. It is often used in hiv infection. eHealthMe is studying from 6,399 Viracept users. Check the latest studies of Viracept.



On Jul, 13, 2026

29 people who take Synthroid and Viracept together, and have interactions are studied.

Synthroid and Viracept drug interactions.

What are the common drug interactions of Synthroid and Viracept, by gender? *:

female:

  1. Abortion spontaneous (naturally occurring miscarriage)
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Anxiety
  4. Back pain
  5. Chronic kidney disease
  6. Emotional distress
  7. Intra-uterine death
  8. Pain
  9. Photosensitivity reaction
  10. Renal pain (kidney pain)

male:

  1. Emotional distress
  2. Pain
  3. Anxiety
  4. Back pain
  5. Blood creatine phosphokinase increased
  6. Decreased activity
  7. Hepatic fibrosis (scarring process that represents the liver's response to injury)
  8. Hepatitis (inflammation of the liver)
  9. Pain in limb
  10. Post-traumatic stress disorder

What are the common drug interactions of Synthroid and Viracept, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Pancarditis (inflammation of the entire heart)
  2. Pancreatitis (inflammation of pancreas)

20-29:

n/a

30-39:

  1. Hypokalaemia (low potassium)
  2. Abortion spontaneous (naturally occurring miscarriage)
  3. Fall
  4. Intra-uterine death
  5. Paralysis
  6. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  7. Blood creatine phosphokinase increased
  8. Dehydration (dryness resulting from the removal of water)
  9. Depression
  10. Dysstasia (difficulty in standing)

40-49:

  1. Photosensitivity reaction
  2. Anaemia (lack of blood)
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Anxiety
  5. Biliary tract disorder
  6. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  7. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  8. Chronic kidney disease
  9. Emotional distress
  10. Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)

50-59:

  1. Hepatic fibrosis (scarring process that represents the liver's response to injury)
  2. Hepatitis (inflammation of the liver)
  3. Anaemia (lack of blood)
  4. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  5. Anxiety
  6. Asthenia (weakness)
  7. Blood creatinine increased
  8. Bone density decreased
  9. Bone marrow failure
  10. Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)

60+:

  1. Back pain
  2. Chronic kidney disease
  3. Anxiety
  4. Renal failure (kidney dysfunction)
  5. Renal pain (kidney pain)
  6. Obesity (having too much body fat)
  7. Renal failure chronic (long lasting kidney dysfunction)
  8. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  9. Weight increased
  10. Emotional distress

What are the existing conditions these people have? *

  1. High Blood Pressure: 5 people, 17.24%
  2. High Blood Cholesterol: 4 people, 13.79%
  3. Diabetes: 4 people, 13.79%
  4. Cardiac Disorder: 4 people, 13.79%
  5. Viral Infection: 3 people, 10.34%
  6. Urinary Retention (the inability to completely or partially empty the bladder): 3 people, 10.34%
  7. Pain: 3 people, 10.34%
  8. Insomnia (sleeplessness): 3 people, 10.34%
  9. Indigestion: 3 people, 10.34%
  10. Hypersensitivity: 3 people, 10.34%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Synthroid and Viracept:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Synthroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Viracept:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Synthroid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Viracept and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium and nelfinavir mesylate (the active ingredients of Synthroid and Viracept, respectively), and Synthroid and Viracept (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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