Tacrolimus and Diamox drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Tacrolimus (tacrolimus) and Diamox (acetazolamide). Common drug interactions include hypophagia among females and cataract among males.
The phase IV clinical study analyzes what interactions people have when they take Tacrolimus and Diamox. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.
What is Tacrolimus?
Tacrolimus has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 116,160 Tacrolimus users. Check the latest studies of Tacrolimus.
What is Diamox?
Diamox has active ingredients of acetazolamide. It is often used in pseudotumor cerebri. eHealthMe is studying from 4,711 Diamox users. Check the latest studies of Diamox.
27 people who take Tacrolimus and Diamox together, and have interactions are studied.

What are the common drug interactions of Tacrolimus and Diamox, by gender? *:
female:
- Hypophagia (reduced food intake)
- Interstitial lung disease
- Mucous membrane disorder (disease of mucous membrane)
- Nausea (feeling of having an urge to vomit)
- Osteonecrosis (death of bone)
- Pneumonia
- Renal disorder (kidney disease)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Urticaria (rash of round, red welts on the skin that itch intensely)
male:
- Cataract (clouding of the lens inside the eye)
- Hypoaesthesia (reduced sense of touch or sensation)
- Rash
- Upper respiratory tract inflammation
- Renal impairment (severely reduced kidney function)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Hepatitis acute
- Liver transplant rejection (failure of liver transplant)
- Headache (pain in head)
- Osteonecrosis (death of bone)
What are the common drug interactions of Tacrolimus and Diamox, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Cardiac failure
- Haematuria (presence of blood in urine)
- Haemorrhage intracranial (bleeding within the skull)
- Histiocytosis haematophagic
- Hypertension (high blood pressure)
- Sepsis (a severe blood infection that can lead to organ failure and death)
20-29:
- Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
- Nausea (feeling of having an urge to vomit)
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Enteritis infectious (infection with feline parvovirus (fpv), also known as feline panleucopenia virus)
30-39:
- Hypoaesthesia (reduced sense of touch or sensation)
- Ocular hypertension (intraocular pressure higher than normal)
- Oral herpes (viral infection of mouth)
- Osteonecrosis (death of bone)
- Pustular psoriasis (raised bumps on the skin that are filled with pus)
- Tremor (trembling or shaking movements in one or more parts of your body)
40-49:
- Osteonecrosis (death of bone)
- Bone density decreased
- Bone loss
- Chronic kidney disease
- Depression
- Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
- Ocular hypertension (intraocular pressure higher than normal)
- Osteomalacia (softening of the bones due to a lack of vitamin d)
- Osteoporosis (bones weak and more likely to break)
- Pathological fracture (broken bone caused by disease)
50-59:
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cataract (clouding of the lens inside the eye)
- Dry eye (lack of adequate tears)
- Gamma-glutamyltransferase increased
- Hypoaesthesia (reduced sense of touch or sensation)
- Intraocular pressure increased
- Muscle spasms (muscle contraction)
- Occult blood (blood in the faeces that is not visibly apparent)
- Oedema peripheral (superficial swelling)
- Rash
60+:
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Hepatitis acute
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
- Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
- Hypoproteinaemia (too little prolactin circulating in the blood)
- Lipase increased
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
- Multi-organ failure (multisystem organ failure)
- Pancreatitis haemorrhagic (inflammation of pancreas with bleeding)
What are the existing conditions these people have? *
- Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 7 people, 25.93%
- Interstitial Lung Disease: 4 people, 14.81%
- Immunodeficiency Disorders: 4 people, 14.81%
- Hiv Infection: 3 people, 11.11%
- Chronic Graft Versus Host Disease (immune cells attack the host's body cells after transplant): 3 people, 11.11%
- Rashes (redness): 2 people, 7.41%
- Pneumonia: 2 people, 7.41%
- Intraocular Pressure Increased: 2 people, 7.41%
- Dry Eyes (lack of adequate tears): 2 people, 7.41%
- Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 2 people, 7.41%
* Approximation only. Some reports may have incomplete information.
Do you take Tacrolimus and Diamox?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Tacrolimus (116,160 reports)
- Diamox (4,711 reports)
Browse all drug interactions of Tacrolimus and Diamox:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tacrolimus:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Diamox:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tacrolimus and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Diamox and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .
- Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .
How the study uses the data?
The study uses data from the FDA. It is based on tacrolimus and acetazolamide (the active ingredients of Tacrolimus and Diamox, respectively), and Tacrolimus and Diamox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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