Tacrolimus and Pataday drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tacrolimus (tacrolimus) and Pataday (olopatadine hydrochloride). Common drug interactions include drug ineffective among females and dermatitis atopic among males.

The phase IV clinical study analyzes what interactions people have when they take Tacrolimus and Pataday. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Tacrolimus?

Tacrolimus has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 116,160 Tacrolimus users. Check the latest studies of Tacrolimus.

What is Pataday?

Pataday has active ingredients of olopatadine hydrochloride. It is often used in allergies. eHealthMe is studying from 8,288 Pataday users. Check the latest studies of Pataday.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

27 people who take Tacrolimus and Pataday together, and have interactions are studied.

Tacrolimus and Pataday drug interactions.

What are the common drug interactions of Tacrolimus and Pataday, by gender? *:

female:

Drug ineffective
Blood pressure increased
Blood cholesterol increased
Diarrhoea
Dupuytren's contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Joint stiffness
Knee arthroplasty
Pain
Pulmonary mass

male:

Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Abscess (pus)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Injection site pain
Lacrimation increased
Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Nausea (feeling of having an urge to vomit)
Nephrogenic anaemia (anaemia due to kidney disease)

What are the common drug interactions of Tacrolimus and Pataday, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Abscess (pus)
Cellulitis (infection under the skin)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Rash

10-19:

Conjunctivitis (pink eye)
Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Erythema (redness of the skin)
Eye pruritus (eye itching)
Lacrimation increased
Nausea (feeling of having an urge to vomit)
Ocular hyperaemia (an abnormally large amount of blood in eye)
Oral herpes (viral infection of mouth)

20-29:

Injection site pain

30-39:

n/a

40-49:

Pain

50-59:

Coma (state of unconsciousness lasting more than six hours)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Headache (pain in head)
Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Nausea (feeling of having an urge to vomit)
Pancreatitis (inflammation of pancreas)
Pneumonia

60+:

Chest pain
Chronic kidney disease
Renal failure (kidney dysfunction)
Tooth disorder (tooth disease)
Drug ineffective
Fluid intake reduced
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypoaesthesia (reduced sense of touch or sensation)
Nephrogenic anaemia (anaemia due to kidney disease)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 29.63%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 8 people, 29.63%
Pain: 3 people, 11.11%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 7.41%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 2 people, 7.41%
Cough: 2 people, 7.41%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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