Tacrolimus and Pentacarinat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tacrolimus (tacrolimus) and Pentacarinat (pentamidine isethionate). Common drug interactions include inflammation among females and stenotrophomonas infection among males.

The phase IV clinical study analyzes what interactions people have when they take Tacrolimus and Pentacarinat. It is created by eHealthMe based on reports of 87 people who take the same drugs from the FDA, and is updated regularly.

What is Tacrolimus?

Tacrolimus has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 116,161 Tacrolimus users. Check the latest studies of Tacrolimus.

What is Pentacarinat?

Pentacarinat has active ingredients of pentamidine isethionate. eHealthMe is studying from 1,546 Pentacarinat users. Check the latest studies of Pentacarinat.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

87 people who take Tacrolimus and Pentacarinat together, and have interactions are studied.

Tacrolimus and Pentacarinat drug interactions.

What are the common drug interactions of Tacrolimus and Pentacarinat, by gender? *:

female:

Inflammation
Myalgia (muscle pain)
Venous injury
Wound secretion
Immunosuppressant drug level increased
Abdominal pain
Acute respiratory distress syndrome
Anaemia (lack of blood)
Epstein-barr virus associated lymphoma (epstein-barr virus associated tumour)
Renal failure (kidney dysfunction)

male:

Stenotrophomonas infection
Neutropenia (an abnormally low number of neutrophils)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Transplant failure (transplantation failed to meet outcome)
Complications of transplanted kidney
Urinary tract infection
Acinetobacter infection (infection by group of bacteria commonly found in soil and water)
Arthralgia (joint pain)
Cardiac failure
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)

What are the common drug interactions of Tacrolimus and Pentacarinat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Epstein-barr virus associated lymphoproliferative disorder (lymphocytes are produced in excessive quantities associated with epstein-barr virus)
Immunosuppressant drug level increased

10-19:

Pancreatitis acute (sudden inflammation of pancreas)

20-29:

Immunosuppressant drug level increased
Anaemia (lack of blood)
Epstein-barr virus associated lymphoma (epstein-barr virus associated tumour)
Renal failure (kidney dysfunction)
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)

30-39:

n/a

40-49:

Headache (pain in head)
Inflammation
Myalgia (muscle pain)
Pyrexia (fever)
Febrile neutropenia (fever with reduced white blood cells)

50-59:

Abdominal pain
Acute respiratory distress syndrome
Death
Anaemia (lack of blood)
Anal abscess
Arrhythmia (irregular heartbeat)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
B-lymphocyte abnormalities (abnormal population of b lymphocytes in the blood, bone marrow, or tissues)
Blood parathyroid hormone decreased
Bone marrow necrosis (death of body tissue of bone marrow)

60+:

Stenotrophomonas infection
Neutropenia (an abnormally low number of neutrophils)
Urinary tract infection
Complications of transplanted kidney
Acinetobacter infection (infection by group of bacteria commonly found in soil and water)
Arthralgia (joint pain)
Cardiac failure
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Drug level fluctuating
Enterococcal infection

What are the existing conditions these people have? *

High Blood Pressure: 29 people, 33.33%
Lung Transplant Rejection (failure of lung transplant): 21 people, 24.14%
Pain: 20 people, 22.99%
Nausea (feeling of having an urge to vomit): 18 people, 20.69%
Febrile Bone Marrow Aplasia (bone marrow greatly decreases or stops production of blood cells): 18 people, 20.69%
Venoocclusive Disease (small veins in the liver are obstructed): 17 people, 19.54%
Fungal Infection: 17 people, 19.54%
Blood Disorder: 17 people, 19.54%
Abdominal Pain Upper: 17 people, 19.54%
Immunodeficiency Disorders: 14 people, 16.09%

* Approximation only. Some reports may have incomplete information.

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