Tacrolimus and Viagra drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Tacrolimus (tacrolimus) and Viagra (sildenafil citrate). Common drug interactions include cardiorenal syndrome among females and renal failure among males.
The phase IV clinical study analyzes what interactions people have when they take Tacrolimus and Viagra. It is created by eHealthMe based on reports of 95 people who take the same drugs from the FDA, and is updated regularly.
What is Tacrolimus?
Tacrolimus has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 116,160 Tacrolimus users. Check the latest studies of Tacrolimus.
What is Viagra?
Viagra has active ingredients of sildenafil citrate. It is often used in erection problems. eHealthMe is studying from 63,865 Viagra users. Check the latest studies of Viagra.
95 people who take Tacrolimus and Viagra together, and have interactions are studied.

What are the common drug interactions of Tacrolimus and Viagra, by gender? *:
female:
- Cardiorenal syndrome (kidney failure and heart failure)
- Chest discomfort
- Claustrophobia (fear of having no escape and being closed in small spaces)
- Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Dyspnoea (difficult or laboured respiration)
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Endometrial cancer
- Endometrial hyperplasia (enlargement of uterus wall)
- Fatigue (feeling of tiredness)
male:
- Renal failure (kidney dysfunction)
- Chronic kidney disease
- Osteoporosis (bones weak and more likely to break)
- Drug ineffective
- Duodenal atresia (absence or complete closure of a portion of the lumen of the duodenum)
- Emotional distress
- Heart rate decreased
- Hot flush (sudden feelings of heat)
- Influenza
- Intestinal obstruction
What are the common drug interactions of Tacrolimus and Viagra, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Abdominal infection
- Abdominal pain upper
- Acidosis (build-up of carbon dioxide in the blood)
- Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
- Asthenia (weakness)
- Back pain
- Blood cholesterol increased
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Bronchopleural fistula
- Cardiac failure congestive
30-39:
- Anxiety
- Chronic kidney disease
- Depression
- Renal failure (kidney dysfunction)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Rash
- Red blood cell count decreased
- Tremor (trembling or shaking movements in one or more parts of your body)
40-49:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Headache (pain in head)
- Pain
- Dysarthria (speech disorder)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
- Arteriovenous malformation
50-59:
- Diarrhoea
- Headache (pain in head)
- Vomiting
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Depressed mood
- Discomfort
- Disturbance in attention
- Drug ineffective
- Emotional disorder
- Emotional distress
60+:
- Renal failure (kidney dysfunction)
- Blood pressure systolic increased
- Anxiety
- Bone density decreased
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Osteoporosis (bones weak and more likely to break)
- Pain
- Pleural effusion (water on the lungs)
- Pulmonary embolism (blockage of the main artery of the lung)
- Dyspnoea (difficult or laboured respiration)
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 18 people, 18.95%
- High Blood Pressure: 17 people, 17.89%
- Pain: 14 people, 14.74%
- Infection: 11 people, 11.58%
- Hiv Infection: 10 people, 10.53%
- High Blood Cholesterol: 10 people, 10.53%
- Stress And Anxiety: 6 people, 6.32%
- Indigestion: 6 people, 6.32%
- Gastrointestinal Disorder (functional problems of gastrointestinal tract): 6 people, 6.32%
- Depression: 6 people, 6.32%
* Approximation only. Some reports may have incomplete information.
Do you take Tacrolimus and Viagra?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Tacrolimus (116,160 reports)
- Viagra (63,865 reports)
Browse all drug interactions of Tacrolimus and Viagra:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tacrolimus:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Viagra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tacrolimus and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Viagra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
- Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on tacrolimus and sildenafil citrate (the active ingredients of Tacrolimus and Viagra, respectively), and Tacrolimus and Viagra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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