Tamoxifen citrate and Zaroxolyn drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tamoxifen citrate (tamoxifen citrate) and Zaroxolyn (metolazone). Common drug interactions include osteonecrosis among females and cardiac arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Tamoxifen citrate and Zaroxolyn. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Tamoxifen citrate?

Tamoxifen citrate has active ingredients of tamoxifen citrate. It is often used in breast cancer. eHealthMe is studying from 11,943 Tamoxifen citrate users. Check the latest studies of Tamoxifen citrate.

What is Zaroxolyn?

Zaroxolyn has active ingredients of metolazone. It is often used in high blood pressure. eHealthMe is studying from 5,244 Zaroxolyn users. Check the latest studies of Zaroxolyn.

On Jul, 13, 2026

28 people who take Tamoxifen citrate and Zaroxolyn together, and have interactions are studied.

Tamoxifen citrate and Zaroxolyn drug interactions.

What are the common drug interactions of Tamoxifen Citrate and Zaroxolyn, by gender? *:

female:

Osteonecrosis (death of bone)
Spinal osteoarthritis (joint cartilage loss in spine)
Acute sinusitis
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arthralgia (joint pain)
Asthenia (weakness)
Balance disorder
Bile duct stenosis (abnormal narrowing of the common bile duct)
Blood calcium increased
Brain neoplasm (tumour of brain)

male:

Cardiac arrest
Blindness transient (sudden loss of vision)

What are the common drug interactions of Tamoxifen Citrate and Zaroxolyn, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Sedation

60+:

Pain
Bone disorder
Acute sinusitis
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arthralgia (joint pain)
Asthenia (weakness)
Balance disorder
Bile duct stenosis (abnormal narrowing of the common bile duct)
Blood calcium increased
Brain neoplasm (tumour of brain)

What are the existing conditions these people have? *

Neoplasm Malignant (cancer tumour): 10 people, 35.71%
Calcium Deficiency (lack of calcium): 10 people, 35.71%
Metastases To Spine (cancer spreads to spine): 10 people, 35.71%
Lung Neoplasm (tumour of lung): 10 people, 35.71%
Pain: 8 people, 28.57%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 6 people, 21.43%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 17.86%
Diabetes: 5 people, 17.86%
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 4 people, 14.29%
Bleeding Disorders: 4 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Tamoxifen citrate and Zaroxolyn?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously