Tarceva and Hydroxyzine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tarceva (erlotinib hydrochloride) and Hydroxyzine (hydroxyzine hydrochloride). Common drug interactions include dizziness among females and rash among males.

The phase IV clinical study analyzes what interactions people have when they take Tarceva and Hydroxyzine. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Tarceva?

Tarceva has active ingredients of erlotinib hydrochloride. It is often used in lung cancer. eHealthMe is studying from 31,036 Tarceva users. Check the latest studies of Tarceva.

What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,069 Hydroxyzine users. Check the latest studies of Hydroxyzine.



On Jul, 28, 2026

50 people who take Tarceva and Hydroxyzine together, and have interactions are studied.

Tarceva and Hydroxyzine drug interactions.

What are the common drug interactions of Tarceva and Hydroxyzine, by gender? *:

female:

  1. Dizziness
  2. Pleural effusion (water on the lungs)
  3. Death
  4. Muscle spasms (muscle contraction)
  5. Nausea (feeling of having an urge to vomit)
  6. Skin burning sensation
  7. Weight decreased
  8. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  9. Ingrowing nail
  10. Pain

male:

  1. Rash
  2. Fatigue (feeling of tiredness)
  3. Muscular weakness (muscle weakness)
  4. Pain
  5. Rash papular (redness with papule)
  6. Diarrhoea
  7. Dry skin
  8. Flatulence (flatus expelled through the anus)
  9. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  10. Hypersensitivity

What are the common drug interactions of Tarceva and Hydroxyzine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Asthenia (weakness)
  2. Decreased appetite
  3. Erythema (redness of the skin)
  4. Fatigue (feeling of tiredness)
  5. Rash erythematous (redness of the skin)
  6. Skin disorder (skin disease)
  7. Vision blurred
  8. Diarrhoea
  9. Pain
  10. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)

60+:

  1. Death
  2. Rash
  3. Oral herpes (viral infection of mouth)
  4. Pleural effusion (water on the lungs)
  5. Dysphagia (a condition in which swallowing is difficult or painful)
  6. Epistaxis (bleed from the nose)
  7. Neck pain
  8. Pain
  9. Swelling
  10. Throat irritation

What are the existing conditions these people have? *

  1. Lung Neoplasm Malignant (cancer tumour of lung): 23 people, 46.00%
  2. Bronchial Carcinoma (lung cancer): 6 people, 12.00%
  3. Nausea (feeling of having an urge to vomit): 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

Do you take Tarceva and Hydroxyzine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tarceva and Hydroxyzine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tarceva:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hydroxyzine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tarceva and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydroxyzine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on erlotinib hydrochloride and hydroxyzine hydrochloride (the active ingredients of Tarceva and Hydroxyzine, respectively), and Tarceva and Hydroxyzine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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